[Regional mesenteric oxygen saturation during blood transfusion in premature neonates].

González Alma Patricia, Miriam Anaya-Solorzano, Luis Enrique Hernández-Díaz, Estefanía Calderón-Ambriz, Víctor Darío López-Flores, Gloria Patricia Sosa-Bustamante, Carlos Paque-Bautista
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引用次数: 0

Abstract

Background: Neonatal anemia (NA) in premature newborns (PTNB) is common and transfusion is one of the treatments of choice; however, it has been associated with the development of necrotizing enterocolitis (NEC).

Objective: To compare regional oxygen saturation (rSO2) and fraction of tissue oxygen excretion (FTOE) at baseline, during and at the end of transfusion in PTNBs with anemia.

Material and methods: Prospective, observational, longitudinal, and analytical study. PTNBs of 28-36 weeks of gestational age (WGA) admitted to a Neonatal Intensive Care Unit (NICU) and with transfusion criteria of Canadian Blood Services were included. rSO2 was measured one hour before, during and up to one hour after transfusion.

Results: 20 PTNBs were analyzed, 3 (15%) girls and 17 (85%) boys, aged 33 WGA (IQR 28-36), postnatal age 31 days (IQR 15-50), and weight of 1815 g (IQR 1385-2520). The rSO2 values before, during and after erythrocyte transfusion were 45.5% (IQR 38.25-60.25), 53.3% (IQR 44.25-64.0) and 53.5% (IQR 50.0-64.25), respectively, F = 5.76, p = 0.006, power = 0.83, DF = 2; FTOE values were 0.50 (IQR 0.31-0.56), 0.42 (IQR 0.30-0.50), and 0.39 (IQR 0.27-0.45), respectively, F = 3.53, p = 0.03, power = 0.62, DF = 2.

Conclusion: Mesenteric rSO2 measurements increased and FTOE decreased gradually before, during and after erythrocyte transfusion, without showing correlation with pretransfusion hemoglobin.

[早产儿输血时肠系膜局部氧饱和度]。
背景:新生儿贫血(NA)在早产新生儿(PTNB)是常见的,输血是治疗的选择之一;然而,它与坏死性小肠结肠炎(NEC)的发展有关。目的:比较ptnb伴贫血患者输血时基线、输血期间和输血结束时的区域氧饱和度(rSO2)和组织氧排泄分数(FTOE)。材料和方法:前瞻性、观察性、纵向和分析性研究。纳入了28-36孕周(WGA)的新生儿重症监护病房(NICU),并符合加拿大血液服务中心的输血标准的ptnb。在输血前1小时、输血中1小时及输血后1小时测量rSO2。结果:共分析20例ptnb,其中女孩3例(15%),男孩17例(85%),年龄33 WGA (IQR 28-36),出生后31天(IQR 15-50),体重1815 g (IQR 1385-2520)。输血前后rSO2值分别为45.5% (IQR 38.25 ~ 60.25)、53.3% (IQR 44.25 ~ 64.0)、53.5% (IQR 50.0 ~ 64.25), F = 5.76, p = 0.006, power = 0.83, DF = 2;FTOE值分别为0.50 (IQR 0.31 ~ 0.56)、0.42 (IQR 0.30 ~ 0.50)、0.39 (IQR 0.27 ~ 0.45), F = 3.53, p = 0.03, power = 0.62, DF = 2。结论:输血前、输血中、输血后肠系膜rSO2逐渐升高,FTOE逐渐降低,与输血前血红蛋白无相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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