A narrative review of the clinical applications of renal NIRS and integration with cerebral NIRS in the NICU.

IF 2.4 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Journal of Perinatology Pub Date : 2025-04-15 DOI:10.1038/s41372-025-02303-3

Dimitrios Rallis, Helen Christou, Elisa Abdulhayoglu, Mohamed El-Dib

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引用次数: 0

Abstract

Organ perfusion and regional tissue oxygen saturation (rSO₂) can be measured non-invasively using near-infrared spectroscopy (NIRS). While cerebral NIRS monitoring in neonates has been widely used, the adoption of renal NIRS is still evolving. This narrative review explores the application of renal NIRS in neonates and proposes an algorithm for integrating renal and cerebral NIRS in the neonatal intensive care unit. Decreased renal regional oxygenation (RrSO₂) suggests decreased renal O₂ delivery/perfusion or increased O₂ consumption, warranting evaluation for acute kidney injury, anemia, hemodynamically significant patent ductus arteriosus, or hypotension. Increased RrSO₂ indicates increased renal O₂ delivery/perfusion or decreased O₂ consumption, necessitating assessment for hyperoxia or established kidney injury. Combining cerebral and renal NIRS provides a comprehensive evaluation, allowing for the detection of early clinical changes. This integrated monitoring approach holds promise for improving neonatal outcomes. However, further large-scale studies are needed to establish normal ranges and guide therapeutic interventions.

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肾NIRS及脑NIRS在新生儿重症监护病房的临床应用综述。

使用近红外光谱（NIRS）可以无创地测量器官灌注和区域组织氧饱和度（rSO2）。虽然新生儿脑近红外光谱监测已被广泛应用，但肾近红外光谱的采用仍在发展中。这篇叙述性的综述探讨了肾脏NIRS在新生儿中的应用，并提出了一种在新生儿重症监护病房中整合肾脏和大脑NIRS的算法。肾区域氧合（RrSO2）降低提示肾氧输送/灌注减少或氧消耗增加，需要对急性肾损伤、贫血、血流动力学显著的动脉导管未闭或低血压进行评估。RrSO2升高表明肾脏氧输送/灌注增加或氧消耗减少，需要评估是否存在高氧或已确定的肾损伤。结合脑和肾近红外光谱提供了一个全面的评估，允许早期临床变化的检测。这种综合监测方法有望改善新生儿结局。然而，需要进一步的大规模研究来确定正常范围并指导治疗干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Perinatology 医学-妇产科学

CiteScore

5.40

自引率

6.90%

发文量

284

审稿时长

3-8 weeks

期刊介绍： The Journal of Perinatology provides members of the perinatal/neonatal healthcare team with original information pertinent to improving maternal/fetal and neonatal care. We publish peer-reviewed clinical research articles, state-of-the art reviews, comments, quality improvement reports, and letters to the editor. Articles published in the Journal of Perinatology embrace the full scope of the specialty, including clinical, professional, political, administrative and educational aspects. The Journal also explores legal and ethical issues, neonatal technology and product development. The Journal’s audience includes all those that participate in perinatal/neonatal care, including, but not limited to neonatologists, perinatologists, perinatal epidemiologists, pediatricians and pediatric subspecialists, surgeons, neonatal and perinatal nurses, respiratory therapists, pharmacists, social workers, dieticians, speech and hearing experts, other allied health professionals, as well as subspecialists who participate in patient care including radiologists, laboratory medicine and pathologists.