Frequency and predictors of risk of non-medical opioid use among patients with cancer in a specialized outpatient palliative care clinic.

IF 2.5 3区医学 Q2 ONCOLOGY

Clinical & Translational Oncology Pub Date : 2025-10-01 Epub Date: 2025-04-19 DOI:10.1007/s12094-025-03929-7

Juan Luis Torres-Tenor, Eduardo Bruera, Inés Sánchez-Mañas, Teresa Pérez-Manrique, Aránzazu Castellano-Candalija, Alberto Alonso-Babarro

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引用次数: 0

Abstract

Purpose: To assess non-medical opioid use (NMOU) risk frequency in outpatients with cancer, compare at-risk vs. non-risk patients, and evaluate the Screener and Opioid Assessment for Patients with Pain-Revised (SOAPP-R) against its shortened version (SOAPP-SF).

Methods: /patients. This cross-sectional study was conducted in a tertiary hospital's palliative care clinic. Adult patients with advanced cancer and cancer pain using or initiating prescribed opioids were included. Patients self-completed the SOAPP-R and SOAPP-SF during consultations. Additional data were gathered from medical records.

Results: A total of 47 patients completed SOAPP-R and SOAPP-SF to assess NMOU risk, with 28% (n = 13) classified as high-risk by both. High-risk patients were younger (p = 0.003), received higher opioid doses (p = 0.026), used more substances (p = 0.018), and were more frequently employed (p = 0.001). SOAPP-SF showed 0.85 specificity, 0.6 sensitivity, 0.85 negative predictive value, and 0.6 positive predictive value compared to SOAPP-R. Both tests agreed on 61.5% of high-risk and 85% of low-risk cases.

Conclusions: Among outpatients with advanced cancer, 28% had high NMOU risk, which was associated with younger age, higher opioid doses, greater substance use, and higher employment rates. SOAPP-SF retained most of the predictive power of the SOAPP-R.

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姑息治疗专科门诊癌症患者非医疗阿片类药物使用的频率和风险预测因素

目的：评估门诊癌症患者非医疗阿片类药物使用（NMOU）的风险频率，比较风险患者与非风险患者，并评估疼痛修正患者筛查和阿片类药物评估（soap -r）与其缩短版本（soap - sf）。方法:/病人。本横断面研究是在三级医院的姑息治疗诊所进行的。使用或启动处方阿片类药物的晚期癌症和癌症疼痛的成年患者被纳入研究。患者在会诊期间自行完成soap - r和soap - sf。从医疗记录中收集了其他数据。结果：共有47例患者完成了soap -r和soap - sf评估NMOU风险，其中28% （n = 13）的患者被两者归为高风险。高危患者更年轻（p = 0.003），接受更高阿片类药物剂量（p = 0.026），使用更多物质（p = 0.018），更频繁地被雇用（p = 0.001）。与soap - r相比，soap - sf的特异性为0.85，敏感性为0.6，阴性预测值为0.85，阳性预测值为0.6。两种检测方法对61.5%的高风险病例和85%的低风险病例的检测结果一致。结论：在晚期癌症门诊患者中，28%的患者NMOU风险较高，这与年龄较小、阿片类药物剂量较高、药物使用较多和就业率较高有关。soap - sf保留了soap - r的大部分预测能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical & Translational Oncology 医学-肿瘤学

CiteScore

6.20

自引率

2.90%

发文量

240

审稿时长

1 months

期刊介绍： Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of new targets for cancer therapy, and new technologies for research and treatment of cancer are the major themes covered by the educational series. Full research articles on a broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.