[Raman microspectroscopy in the diagnosis of skin malignancies].

Q3 Medicine

Vestnik otorinolaringologii Pub Date : 2025-01-01 DOI:10.17116/otorino20259002137

A B Timurzieva, V I Popadiuk, M S Fedina, E N Rimskaya, S N Shelygina, K G Kudrin

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引用次数: 0

Abstract

Introduction: The development of methods for early diagnosis of tumor diseases of the head and neck is one of the most important areas of biomedicine and healthcare in general. Special attention should be paid to consideration of issues related to the diagnosis of malignant neoplasms of the skin of the head and neck area. In this aspect, confocal Raman microspectroscopy is of interest.

Objective: To demonstrate the feasibility of using Raman microspectroscopy to differentiate intact skin from malignant skin neoplasms.

Material and methods: The study used Raman microspectroscopy with an excitation wavelength of 532 nm to diagnose basal cell carcinoma and squamous cell carcinoma of the skin and differentiate them from intact skin.

Results: During the study, spectra of intact skin and skin neoplasms in the head and neck region (basal cell and squamous cell carcinoma of the skin) were obtained.

Conclusion: The results of the study can be used in the future for optical biopsy and early diagnosis of tumors.

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[拉曼显微光谱在皮肤恶性肿瘤诊断中的应用]。

前言：头颈部肿瘤疾病早期诊断方法的发展是生物医学和医疗保健的重要领域之一。应特别注意考虑与头颈部皮肤恶性肿瘤诊断有关的问题。在这方面，共聚焦拉曼显微光谱学引起了人们的兴趣。目的：探讨利用拉曼光谱技术鉴别完整皮肤与皮肤恶性肿瘤的可行性。材料与方法：本研究采用激发波长为532 nm的拉曼显微光谱对皮肤基底细胞癌和鳞状细胞癌进行诊断，并与完整皮肤进行鉴别。结果：在研究过程中，获得了完整皮肤和头颈部皮肤肿瘤（皮肤基底细胞癌和鳞状细胞癌）的光谱。结论：本研究结果可用于光学活检及肿瘤的早期诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vestnik otorinolaringologii Medicine-Otorhinolaryngology

CiteScore

0.80

自引率

0.00%

发文量