The Association between Obesity and Wet Overactive Bladder: Results from 2005 to 2020 National Health and Nutrition Examination Survey.

IF 3.9 3区医学 Q2 ENDOCRINOLOGY & METABOLISM

Obesity Facts Pub Date : 2025-05-11 DOI:10.1159/000546104

Jiahao Zhang, Wanru Chen, Zhicheng Tang, Xuqing Lin, Xitong Wan, Shuqiang Huang, Hongcheng Luo, Yuxin Qian, Zhaohui He, Fucai Tang

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引用次数: 0

Abstract

Introduction: The association between obesity and wet overactive bladder (wet OAB) was few and was also inconsistent and controversial in sex differences. This study aimed to ascertain the specific association between obesity and wet OAB for females and males using five obesity measures.

Methods: This cross-sectional study included 29,041 participants from the 2005-2020 National Health and Nutrition Examination Survey database. The outcome was the risk of wet OAB. Five obesity measures were exposure using quintile, including body mass index (BMI), waist-to-stature ratio (WSR), body fat percentage (BFP), fat mass, and lean mass. The associations were elucidated using weighted logistic regression models and restricted cubic spline (RCS) analysis.

Results: The elevated BMI, WSR, BFP, and fat mass were positively associated with the risk of wet OAB in both sexes, which was evident in females. Interestingly, lean mass was adversely associated with the risk of wet OAB in both sexes. In RCS analysis about BMI, WSR, BFP, and fat mass, monotonically increasing nonlinear associations were found in males, while positive linear associations were found in females. Besides, negative linear and nonlinear relationships were shown between lean mass and the risk of wet OAB in females and males, respectively.

Conclusions: Obesity was positively associated with the risk of wet OAB in both sexes. Controlling BMI, WSR, BFP, fat mass, and strengthening lean mass may help prevent the development of wet OAB.

查看原文本刊更多论文

肥胖与湿性膀胱过动症的关系：2005-2020年全国健康与营养调查结果

摘要：肥胖与湿性膀胱过动症（wet overactive膀胱，wet OAB）之间的关联较少，在性别差异上也存在不一致和争议。本研究旨在通过五种肥胖测量来确定女性和男性肥胖与湿OAB之间的具体联系。方法：本横断面研究纳入了2005-2020年全国健康与营养检查调查数据库中的29,041名参与者。结果是湿OAB的风险。五种肥胖测量方法采用五分位数，包括体重指数（BMI）、腰高比（WSR）、体脂率（BFP）、脂肪质量和瘦质量。使用加权逻辑回归模型和限制三次样条分析来阐明这些关联。结果：BMI、WSR、BFP和脂肪量的升高与湿性OAB的风险呈正相关，这在女性中很明显。有趣的是，无论男女，瘦质量与湿性OAB的风险呈负相关。在BMI、WSR、BFP和脂肪质量的限制性三次样条（RCS）分析中，男性呈单调递增的非线性相关，而女性呈线性正相关。此外，女性和男性的瘦质量与湿性OAB风险分别呈负线性和非线性关系。结论：无论男女，肥胖与湿性OAB的风险呈正相关。控制BMI、WSR、BFP、脂肪量和加强瘦体重可能有助于预防湿性OAB的发展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity Facts 医学-内分泌学与代谢

CiteScore

6.80

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： ''Obesity Facts'' publishes articles covering all aspects of obesity, in particular epidemiology, etiology and pathogenesis, treatment, and the prevention of adiposity. As obesity is related to many disease processes, the journal is also dedicated to all topics pertaining to comorbidity and covers psychological and sociocultural aspects as well as influences of nutrition and exercise on body weight. The editors carefully select papers to present only the most recent findings in clinical practice and research. All professionals concerned with obesity issues will find this journal a most valuable update to keep them abreast of the latest scientific developments.