Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at referral hospitals of amhara regional state, institutional-based cross-sectional study, North-West Ethiopia.

IF 2.3 Q2 OBSTETRICS & GYNECOLOGY
Frontiers in global women's health Pub Date : 2025-03-27 eCollection Date: 2025-01-01 DOI:10.3389/fgwh.2025.1555778
Misganaw Fikrie Melesse, Getie Lake Aynalem, Martha Berta Badi, Bewket Yeserah Aynalem
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引用次数: 0

Abstract

Introduction: Severe preeclampsia/eclampsia is a multi-systemic pregnancy condition that manifests after 20 weeks of gestation and is linked to a high global rate of maternal morbidity and mortality. It is responsible for 11%-14% of maternal mortality globally and is the second most frequent direct obstetrical cause of death. This study aimed to assess maternal outcomes of severe preeclampsia/eclampsia and associated factors in mothers admitted to referral hospitals in the Amhara Regional State of North West Ethiopia.

Methods: An institutionally based cross-sectional investigation on the outcomes of severe preeclampsia/eclampsia in mothers was carried out from April 1 to September 30, 2018. Using the census sampling technique, 456 study participants were included in the study. Data were coded, verified, and imported into Epi-info version 7.2 before being exported and analyzed in SPSS version 26. To determine the determinants of maternal outcomes of severe preeclampsia or eclampsia, binary logistic regression was employed, with a significance level of 95% confidence interval of odds ratio at p-value 0.05 or below.

Results: Overall, severe preeclampsia and eclampsia were shown to have unfavorable maternal outcomes in 37.7% (95% CI: 32.8%, 42.3%). The following variables had statistically significant associations with unfavorable maternal outcomes of severe preeclampsia and eclampsia: educational status (AOR = 4.5, 95% CI: 1.95, 12.31), residence (AOR = 2.1, 95% CI: 1.17, 3.72), monthly family income (AOR = 2.7, 95% CI: 1.25, 6.12), parity (AOR = 6.7, 95% CI: 1.55, 12.6), history of abortion (AOR = 3.5, 95% CI: 1.63, 7.58), booking status (AOR = 5.8, 95% CI: 3.15, 9.72), and time of drug given (AOR = 4.9, 95% CI: 1.86, 13.22).

Conclusion: It was discovered that severe preeclampsia and eclampsia had a high overall rate of unfavorable maternal outcomes. Promoting early antenatal care booking and formal education for women can reduce preeclampsia and eclampsia outcomes.

埃塞俄比亚西北部阿姆哈拉地区州转诊医院收治妇女的严重先兆子痫和子痫的产妇结局及相关因素,基于机构的横断面研究。
重度子痫前期/子痫是一种多系统妊娠疾病,在妊娠20周后表现出来,与全球孕产妇发病率和死亡率高有关。它占全球孕产妇死亡率的11%-14%,是第二大最常见的直接产科死亡原因。本研究旨在评估埃塞俄比亚西北部阿姆哈拉地区州转诊医院收治的严重先兆子痫/子痫母亲的结局及其相关因素。方法:对2018年4月1日至9月30日重度先兆子痫/子痫母亲的结局进行基于机构的横断面调查。采用人口普查抽样技术,共纳入456名研究对象。将数据编码、验证并导入Epi-info 7.2版本,然后在SPSS 26版本中导出和分析。为确定重度子痫前期或子痫产妇结局的决定因素,采用二元logistic回归,优势比95%置信区间的显著性水平为p值0.05或以下。结果:总体而言,37.7%的严重子痫前期和子痫表现出不良的产妇结局(95% CI: 32.8%, 42.3%)。下列变量有显著关联不宜孕产妇严重子痫前期和子痫的结果:教育地位(AOR = 4.5, 95% CI: 1.95, 12.31),住所(AOR = 2.1, 95% CI: 1.17, 3.72),每月家庭收入(优势比= 2.7,95% CI: 1.25, 6.12),平价(AOR = 6.7, 95% CI: 1.55, 12.6),堕胎的历史(AOR = 3.5, 95% CI: 1.63, 7.58),预订状态(AOR = 5.8, 95% CI: 3.15, 9.72),给药物的和时间(AOR = 4.9, 95% CI: 1.86, 13.22)。结论:重度先兆子痫及子痫患儿不良结局发生率较高。促进早期产前保健预约和对妇女进行正规教育可以减少子痫前期和子痫结局。
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来源期刊
CiteScore
3.70
自引率
0.00%
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审稿时长
13 weeks
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