Regenerative mechanisms of stem cells and their clinical applications for degenerative eye diseases.

IF 1.5 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Journal of Research in Medical Sciences Pub Date : 2024-07-30 eCollection Date: 2024-01-01 DOI:10.4103/jrms.jrms_358_23
Baodong Zhang, Shusong Gao, Shibo Liu, Xuewu Gong, Jing Wu, Yu Zhang, Li Ma, Lijie Sheng
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引用次数: 0

Abstract

There are different types of treatment for eye diseases. Although the majority of eye diseases are curable with primary treatments and surgery, some of degenerative eye damages need regeneration that is not gained by conventional procedures. Stem cells, such as mesenchymal stem cells, human embryonic stem cell-derived retinal pigmented epithelium, and inducible pluripotent stem cells, are now considered one of the most important and safe methods for regeneration of various damaged tissues or organs. However, how will stem cell therapy contribute to regeneration and overcome degenerative eye diseases? This review discusses the regenerative mechanisms, clinical applications, and advantages of different types of stem cells for restoring degenerative eye diseases.

干细胞再生机制及其在退行性眼病中的临床应用。
眼病有不同的治疗方法。虽然大多数眼病可以通过初级治疗和手术治愈,但一些退行性眼睛损伤需要再生,这是传统手术无法获得的。干细胞,如间充质干细胞、人胚胎干细胞衍生的视网膜色素上皮和诱导多能干细胞,目前被认为是各种受损组织或器官再生的最重要和最安全的方法之一。然而,干细胞治疗如何有助于再生和克服退行性眼病?本文就不同类型干细胞的再生机制、临床应用及在退行性眼病修复中的优势作一综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Research in Medical Sciences
Journal of Research in Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
2.60
自引率
6.20%
发文量
75
审稿时长
3-6 weeks
期刊介绍: Journal of Research in Medical Sciences, a publication of Isfahan University of Medical Sciences, is a peer-reviewed online continuous journal with print on demand compilation of issues published. The journal’s full text is available online at http://www.jmsjournal.net. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles on any OAI-compliant institutional / subject-based repository.
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