DEMOGRAPHIC PROFILE, SUBSTANCE USE TRENDS AND ASSOCIATED PSYCHOTIC DISORDERS AMONG VETERANS WITH MENTAL HEALTH CONDITIONS: A RETROSPECTIVE COHORT STUDY OF US VETERANS.

IF 0.1 Q4 PSYCHIATRY
Jason Obermann, Krishna Divadeenam, Alexandra V Flynn, Hemant Thakur, Vikas Singh, Rishi Sharma, Thomas Wiegmann, Varun Boinpelly, Kenneth Grasing, Mukut Sharma, Ram Sharma
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Abstract

Background: Amphetamine and other substances induced psychotic disorder and associated suicidal risk among hospitalized US veterans is not clear.

Aims: To understand the demographic profile, substance use trends, psychotic disorders and suicide attempts in veterans hospitalized with acute Mental Health Conditions (MHC).

Methods: Veterans Affairs Informatics and Computing Infrastructure Database (ICD) and codes were used to identify veterans hospitalized with MHC diagnosis between 1999 and 2022. Laboratory records used to determine types of substances used hospitalization frequency, all-cause mortality, suicide attempts and suicide outcomes. SAS was used for statistical analysis.

Results: Among veterans with MHC, psychosis, manic-bipolar and PTSD were common diagnosis. Psychosis was comparatively less among males above 50 years of age, but prevalent among Hispanics. In general, substances use was significantly higher, and amphetamines were most used, followed by cannabis codeine, morphine, cocaine, barbiturates, fentanyl, and PCP among veterans with MHC. Amphetamine induced psychotic disorder persisted in 22.28% and other substance induced psychotic disorder persisted in 77.72% of veterans hospitalized with MHC. Psychosis was associated with higher rates of hospitalization, suicide attempts, and suicide death.

Conclusions: Among US Veterans with MHC, amphetamine was most used substance associated with higher rates of psychotic disorders, hospitalization, suicide attempts, and death.

具有精神健康状况的退伍军人的人口统计资料、物质使用趋势和相关精神障碍:一项对美国退伍军人的回顾性队列研究
背景:安非他明和其他物质在住院美国退伍军人中诱发精神障碍和相关自杀风险尚不清楚。目的:了解急性精神健康状况(MHC)住院退伍军人的人口统计特征、物质使用趋势、精神障碍和自杀企图。方法:利用退伍军人事务信息与计算基础设施数据库(ICD)和代码对1999 - 2022年诊断为MHC的住院退伍军人进行识别。用于确定所用物质类型的实验室记录住院频率、全因死亡率、自杀企图和自杀结果。采用SAS进行统计分析。结果:在MHC退伍军人中,精神病、躁郁症和创伤后应激障碍是常见的诊断。精神病在50岁以上的男性中相对较少,但在西班牙裔人中普遍存在。总的来说,药物的使用明显更高,在患有MHC的退伍军人中,安非他明的使用最多,其次是大麻可待因、吗啡、可卡因、巴比妥酸盐、芬太尼和PCP。因MHC住院的退伍军人中,苯丙胺诱发的精神障碍持续存在的占22.28%,其他物质诱发的精神障碍持续存在的占77.72%。精神病与较高的住院率、自杀未遂率和自杀死亡率有关。结论:在患有MHC的美国退伍军人中,安非他明是与较高的精神障碍、住院、自杀企图和死亡发生率相关的最常用物质。
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