{"title":"GPU accelerated internal dose Monte Carlo simulation in 18F-FDG PET imaging.","authors":"Zhiyuan Yang, Zhiling Li, Weihai Zhuo, Lin Xin","doi":"10.1093/rpd/ncaf038","DOIUrl":null,"url":null,"abstract":"<p><p>Estimation of radiation dose from diagnostic or therapeutic radiopharmaceuticals in humans has drawn great interests. A graphics processing units based (GPU-based) positron and photon coupling transport code was developed for rapid calculation of the internal irradiation dose map. PENELOPE random hinge model was used to calculate the multi-scattering problem. More than 90% of the organ dose differences compared with GATE are within 1%. The average organ dose difference is 0.651%. The calculation time for 1E8 particles is only 321 s, and the calculation time for 1E7 particles is only 35 s, which is only 0.1% of GATE. simulation accuracy and acceleration efficiency of this study are both significantly improved compared with other GPU-based internal dosimetry Monte Carlo simulation code. This work can help to develop a more patient-specific, accurate, efficient way to improve the speed of PET/CT dosimetry Monte Carlo simulation.</p>","PeriodicalId":20795,"journal":{"name":"Radiation protection dosimetry","volume":"201 6","pages":"450-460"},"PeriodicalIF":0.8000,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation protection dosimetry","FirstCategoryId":"93","ListUrlMain":"https://doi.org/10.1093/rpd/ncaf038","RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENVIRONMENTAL SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Estimation of radiation dose from diagnostic or therapeutic radiopharmaceuticals in humans has drawn great interests. A graphics processing units based (GPU-based) positron and photon coupling transport code was developed for rapid calculation of the internal irradiation dose map. PENELOPE random hinge model was used to calculate the multi-scattering problem. More than 90% of the organ dose differences compared with GATE are within 1%. The average organ dose difference is 0.651%. The calculation time for 1E8 particles is only 321 s, and the calculation time for 1E7 particles is only 35 s, which is only 0.1% of GATE. simulation accuracy and acceleration efficiency of this study are both significantly improved compared with other GPU-based internal dosimetry Monte Carlo simulation code. This work can help to develop a more patient-specific, accurate, efficient way to improve the speed of PET/CT dosimetry Monte Carlo simulation.
期刊介绍：
Radiation Protection Dosimetry covers all aspects of personal and environmental dosimetry and monitoring, for both ionising and non-ionising radiations. This includes biological aspects, physical concepts, biophysical dosimetry, external and internal personal dosimetry and monitoring, environmental and workplace monitoring, accident dosimetry, and dosimetry related to the protection of patients. Particular emphasis is placed on papers covering the fundamentals of dosimetry; units, radiation quantities and conversion factors. Papers covering archaeological dating are included only if the fundamental measurement method or technique, such as thermoluminescence, has direct application to personal dosimetry measurements. Papers covering the dosimetric aspects of radon or other naturally occurring radioactive materials and low level radiation are included. Animal experiments and ecological sample measurements are not included unless there is a significant relevant content reason.
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