Dyskinesia-Hyperpyrexia Syndrome in Parkinson's Disease May Benefit from GPi Deep Brain Stimulation: A Case Report.

IF 2.5 Q2 CLINICAL NEUROLOGY

Tremor and Other Hyperkinetic Movements Pub Date : 2025-05-07 eCollection Date: 2025-01-01 DOI:10.5334/tohm.912

Shi-Shi Huang, Lu-Lu Ma, Han-Song Sheng, Rong-Pei Liu, Shi-Guo Zhu, Shan-Shan Xu, Mei-Ling Sheng, Zhu-Ling Chen, Nu Zhang, Xiong Zhang, Jian-Yong Wang

引用次数: 0

Abstract

Background: Dyskinesia-hyperpyrexia syndrome (DHS) is a rare but life-threatening complication in Parkinson's disease (PD). Its prevention and treatment are clinical challenges.

Case report: We herein present a case of a female PD patient who experienced recurrent episodes of DHS and levodopa-induced dyskinesia. The complications were alleviated after bilateral globus pallidus internus (GPi) deep brain stimulation (DBS).

Discussion: Our report provides evidence that GPi DBS may reduce the susceptibility to DHS. More evidences are warranted to validate this hypothesis.

查看原文本刊更多论文

帕金森病运动障碍-高热综合征可能受益于GPi深部脑刺激：一例报告。

背景：运动障碍-高热综合征（DHS）是帕金森病（PD）中一种罕见但危及生命的并发症。其预防和治疗是临床面临的挑战。病例报告：我们在此报告一例女性PD患者，她经历了DHS和左旋多巴诱导的运动障碍的反复发作。双侧内苍白球（GPi）深部脑刺激（DBS）术后并发症明显减轻。讨论：我们的报告提供了GPi DBS可能降低DHS易感性的证据。有更多的证据可以证实这一假设。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊