Short-term health effects of tear agents chlorobenzylidenemalononitrile and oleoresin capsicum during the civil riots of Santiago de Chile in 2019-2020.

IF 1.6 4区 医学 Q4 TOXICOLOGY
Toxicological Research Pub Date : 2025-02-27 eCollection Date: 2025-05-01 DOI:10.1007/s43188-025-00282-3
Carlos Jara Bravo, José Antonio Cernuda Martínez, Pedro Arcos González
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Abstract

Chlorobenzylidenemalononitrile (CS) and Oleoresin Capsicum (OC) were tear gasses used as anti-riot control agents during social unrest riots in Chile (October 2019-March 2020). This study posed as a research question what were the short-term health effects of CS and OC and their patterns of temporal occurrence in a sample of inhabitants and health care volunteer brigades of the Plaza Italia (city of Santiago, Chile) during the riots. A retrospective cross-sectional study was conducted in 112 exposed people (inhabitants and health care volunteers) affected by CS and OC. 62 harmful effects were studied classified in three time periods of occurrence: immediate effects (between exposure and one hour), secondary effects (from one hour after exposure and up to 24 h), and subsequent effects (days after exposure). The use of CS and OC in Santiago riots 2019-2020 produced harmful effects on both groups: inhabitants and brigade health care volunteers. The frequency of effects was, from most to least common: 62.5% eye pain or burning, 56.2% throat irritation, 54.4% respiratory distress, 52.6% skin pain or burning, 51.7% impaired vision, 37.5% skin erythema, 31.2% headache, 31.2% irregular breathing, 25.8% conjunctival injection, 29.4% nausea, 27.6% disorientation, 26.7 high blood pressure, 25.8% lip pain, 24.1% rhinitis, 24.1% skin sensitivity, 22.3% diarrhea, 20.5% contact dermatitis, 18.7% conjunctivitis, 16.9% skin vesicles, 16% tachycardia, 14.4 cough with phlegm and 9.8% corneal abrasion. 22 effects were more frequent (p < 0.05) in health care volunteers than among residents. High blood pressure was more frequent (p < 0.05) among residents. Immediate most frequent effects were pain or burning, impaired vision, respiratory difficulty, irregular breathing, skin pain and burning, skin erythema, nausea, tachycardia, and hypertension. Secondary effects were diarrhea, skin vesicles, and eye pain or burning. Subsequent most frequent effects among healthcare personnel were conjunctivitis, skin pain, burning, rhinitis, and diarrhea. Among residents, the most common effects were skin pain, burning, and impaired vision.

2019-2020年智利圣地亚哥骚乱期间撕裂剂氯乙二烯丙腈和辣椒油树脂对健康的短期影响
在2019年10月至2020年3月的智利社会骚乱中,氯乙二烯丙二腈(CS)和辣椒油树脂(OC)被用作防暴催泪弹。本研究提出了一个研究问题,在骚乱期间,在意大利广场(智利圣地亚哥市)的居民和卫生保健志愿者队伍样本中,CS和OC的短期健康影响及其时间发生模式是什么。对112名受CS和OC影响的暴露者(居民和卫生保健志愿者)进行了回顾性横断面研究。对62种有害影响进行了研究,并将其分为三个发生时间段:立即影响(接触后1小时至24小时)、继发性影响(接触后1小时至24小时)和后续影响(接触后几天)。在2019-2020年圣地亚哥骚乱中使用CS和OC对居民和旅卫生保健志愿者这两个群体都产生了有害影响。影响的频率从最常见到最不常见:62.5%眼睛疼痛或灼烧、56.2%喉咙刺激、54.4%呼吸窘迫、52.6%皮肤疼痛或灼烧、51.7%视力受损、37.5%皮肤红斑、31.2%头痛、31.2%呼吸不规则、25.8%结膜注射、29.4%恶心、27.6%定向障碍、26.7高血压、25.8%唇痛、24.1%鼻炎、24.1%皮肤敏感、22.3%腹泻、20.5%接触性皮炎、18.7%结膜炎、16.9%皮肤小泡、16%心动过速、14.4咳嗽伴痰、9.8%角膜擦伤。22种影响更频繁(p
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来源期刊
CiteScore
4.20
自引率
4.30%
发文量
39
期刊介绍: Toxicological Research is the official journal of the Korean Society of Toxicology. The journal covers all areas of Toxicological Research of chemicals, drugs and environmental agents affecting human and animals, which in turn impact public health. The journal’s mission is to disseminate scientific and technical information on diverse areas of toxicological research. Contributions by toxicologists, molecular biologists, geneticists, biochemists, pharmacologists, clinical researchers and epidemiologists with a global view on public health through toxicological research are welcome. Emphasis will be given to articles providing an understanding of the toxicological mechanisms affecting animal, human and public health. In the case of research articles using natural extracts, detailed information with respect to the origin, extraction method, chemical profiles, and characterization of standard compounds to ensure the reproducible pharmacological activity should be provided.
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