Incidence and Survival Trends of Cervical Cancer in Khon Kaen, Thailand.

Q2 Medicine

Asian Pacific Journal of Cancer Prevention Pub Date : 2025-04-01 DOI:10.31557/APJCP.2025.26.4.1393

Jakkree Pasane, Kan Sriwatana, Kuntawit Krasairsom, Napatsanun Suwunnapang, Chalongpon Santong, Bandit Chumworathayi

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引用次数: 0

Abstract

Objective: To evaluate and report the incidence and survival trends of cervical cancer in Khon Kaen, Thailand, during 1991-2020.

Methods: A retrospective study was conducted by using the electronic cancer registry database of Khon Kaen province population. Joinpoint regression model was used to analyze the Age-Standardized Incidence Rate (ASR) and the incidence trend graph was built. Overall Observed Survival (OS) was analyzed by Kaplan Meier method and the survival trend graph was built similarly.

Result: During 1991-2020, 3,071 cervical cancer patients were found in Khon Kaen. Their mean age was 51.7 year-old. The ASR had decreased from 13.51 (95%CI: 10.67-16.35) per 100,000 women-year in 1991 to 7.63 (95%CI: 5.93-9.33) per 100,000 women-year in 2020. This trend was consistent with the country's and international trends. The highest incidence was found in 1993, which was 17.73 (95%CI: 14.65-20.81), and the lowest incidence was found in 2016, which was 5.7 (95%CI: 4.30-7.10) per 100,000 women-year. However, the 5-year OS was 48.37% (95%CI: 46.49-50.22), which was a constant trend. At the beginning in 1991-1995, the OS was 40.31% (95%CI: 35.43-45.12), and at the end in 2016-2020, the OS was 40.46% (95%CI: 34.59-46.23). These were very similar.

Conclusion: In Khon Kaen, Thailand, during 1991-2020, the cervical cancer incidence (ASR) trend was decreasing, while the cervical cancer survival (OS) trend was constant. WHO elimination of cervical cancer initiative target should be reached by 2030.

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泰国孔敬地区宫颈癌的发病率和生存趋势。

目的：评价和报道1991-2020年泰国孔敬地区宫颈癌的发病率和生存趋势。方法：采用孔敬省人口癌症电子登记数据库进行回顾性研究。采用关节点回归模型对年龄标准化发病率（ASR）进行分析，建立发病率趋势图。采用Kaplan Meier法分析总观察生存率（Overall Observed Survival， OS），并绘制生存趋势图。结果：1991-2020年，孔敬县共发现宫颈癌患者3071例。他们的平均年龄为51.7岁。ASR从1991年的13.51 (95%CI: 10.67-16.35) / 10万妇女年下降到2020年的7.63 (95%CI: 5.93-9.33) / 10万妇女年。这一趋势与国家和国际趋势是一致的。1993年发病率最高，为17.73例（95%CI: 14.65 ~ 20.81）， 2016年发病率最低，为5.7例(95%CI: 4.30 ~ 7.10) / 10万妇女年。但5年OS为48.37% (95%CI: 46.49 ~ 50.22)，趋势不变。1991-1995年初OS为40.31% (95%CI: 35.43-45.12)， 2016-2020年末OS为40.46% （95%CI: 34.59-46.23）。它们非常相似。结论：1991-2020年，泰国孔景县宫颈癌发病率（ASR）呈下降趋势，而宫颈癌生存率（OS）呈稳定趋势。到2030年应实现世卫组织消除宫颈癌行动的目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Asian Pacific Journal of Cancer Prevention 医学-肿瘤学

CiteScore

2.80

自引率

0.00%

发文量

779

审稿时长

3 months

期刊介绍： Cancer is a very complex disease. While many aspects of carcinoge-nesis and oncogenesis are known, cancer control and prevention at the community level is however still in its infancy. Much more work needs to be done and many more steps need to be taken before effective strategies are developed. The multidisciplinary approaches and efforts to understand and control cancer in an effective and efficient manner, require highly trained scientists in all branches of the cancer sciences, from cellular and molecular aspects to patient care and palliation. The Asia Pacific Organization for Cancer Prevention (APOCP) and its official publication, the Asia Pacific Journal of Cancer Prevention (APJCP), have served the community of cancer scientists very well and intends to continue to serve in this capacity to the best of its abilities. One of the objectives of the APOCP is to provide all relevant and current scientific information on the whole spectrum of cancer sciences. They aim to do this by providing a forum for communication and propagation of original and innovative research findings that have relevance to understanding the etiology, progression, treatment, and survival of patients, through their journal. The APJCP with its distinguished, diverse, and Asia-wide team of editors, reviewers, and readers, ensure the highest standards of research communication within the cancer sciences community across Asia as well as globally. The APJCP publishes original research results under the following categories: -Epidemiology, detection and screening. -Cellular research and bio-markers. -Identification of bio-targets and agents with novel mechanisms of action. -Optimal clinical use of existing anti-cancer agents, including combination therapies. -Radiation and surgery. -Palliative care. -Patient adherence, quality of life, satisfaction. -Health economic evaluations.