Comparison of Microwave Ablation and Lobectomy in the Treatment of Benign Thyroid Nodules.

IF 1.2 4区医学 Q3 ACOUSTICS

Journal of Clinical Ultrasound Pub Date : 2025-05-12 DOI:10.1002/jcu.24071

Saim Turkoglu, Abdullah Hilmi Yilmaz, Adem Yokus, Mehmet Eşref Ulutaş

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引用次数: 0

Abstract

Purpose: The purpose of this study is to evaluate the efficacy, safety, and advantages of microwave ablation (MWA) compared to lobectomy in the treatment of benign thyroid nodules.

Methods: A total of 105 patients were included in the study, 49 in the MWA group and 56 in the surgical group. The mean age of the patients in the MWA group was 49.5 (±12.8) and 40.2 (±10.1) in the surgical group (p < 0.001). 81.6% of the patients in the MWA group were female and 18.4% were male. 83.9% of the patients in the surgical group were male and 16.1% were female (p = 0.75). Patients were followed for at least 12 months. The study was completed by comparing the two groups in terms of surgery-procedure times, complications, nodule sizes, thyroid function tests, symptoms, volume reduction rates (VRR), and cosmetic improvement scores.

Results: The mean maximum nodule diameter in the patient group who underwent MWA was 3.5 (±1) cm at the beginning and 2.3 (±0.9) cm at the end of the 12th month (p < 0.001). VRR was 73.4% (±14.8) at the end of the 12th month (p < 0.001). Cosmetic score was 2.5 (±1) at the first month, 1.7 (±1.1) at the third month, 1 (±1) at the sixth month, and 0.6 (±0.7) at the 12th month (p < 0.001). The procedure time was 15.4 (±4.4) minutes in the patients in the MWA group, while it was 70.7 (±17.2) minutes in the surgical group (p < 0.001). No complications developed in 48 patients (98%) in the MWA group and 38 patients (67.9%) in the surgical group (p = 0.005). Voice change occurred in three patients (5.4%) in the surgical group, hematoma in two (3.6%) patients and voice change in one (1.8%) patient in the MWA group. Hypothyroidism developed in eight patients in the surgical group, while hypothyroidism did not develop in the MWA group (p = 0.007).

Conclusion: MWA is a safe and effective treatment method for benign thyroid nodules. It has many advantages over thyroidectomy, such as fewer complications, shorter procedure time, no need for hospitalization and general anesthesia, and good cosmetic results.

Clinical significance: Compared with surgery, MWA is a safe, effective, and cost-effective treatment for benign thyroid nodules.

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微波消融与肺叶切除术治疗良性甲状腺结节的比较。

目的：本研究的目的是评价微波消融（MWA）治疗良性甲状腺结节的疗效、安全性和优点，并与肺叶切除术进行比较。方法：共纳入105例患者，其中MWA组49例，手术组56例。MWA组患者的平均年龄为49.5（±12.8）岁，手术组患者的平均年龄为40.2（±10.1）岁(p)结果：MWA组患者的平均最大结节直径开始时为3.5（±1）cm， 12个月结束时为2.3（±0.9）cm (p)结论：MWA是治疗良性甲状腺结节安全有效的方法。与甲状腺切除术相比，它有许多优点，如并发症少，手术时间短，不需要住院和全身麻醉，美容效果好。临床意义：与手术相比，MWA是一种安全、有效、经济的治疗良性甲状腺结节的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Clinical Ultrasound 医学-核医学

CiteScore

1.90

自引率

0.00%

发文量

248

审稿时长

6 months

期刊介绍： The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.