Burden of non-communicable diseases in South Asia: a decomposition analysis.

IF 2.4 3区 医学 Q3 ENVIRONMENTAL SCIENCES
Jalandhar Pradhan, Manacy Pai, Rinshu Dwivedi, Bijeta Mishra, Sasmita Behera, Tapas Bera, Rockli Kim, S V Subramanian
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引用次数: 0

Abstract

Background: This study examines the incidence, prevalence, deaths, and disability-adjusted life years (DALYs) related to non-communicable diseases (NCDs) in South Asia, exploring the environmental, metabolic, and behavioural risk factors, and exploring changes in deaths and DALYs driven by population growth, aging, and mortality rates.

Methods: Using data from the Global Burden of Disease (GBD) study 2021, we estimated age-standardized incidence, prevalence, deaths, and DALYs for four major NCDs: cardiovascular diseases, cancer, diabetes, and chronic respiratory diseases from 2010 to 2021. Gender and age-specific estimations were conducted across all NCDs, with 95% uncertainty intervals and a decomposition analysis was employed to estimate change in death and DALYs attributable to NCDs.

Findings: The burden of NCDs in South Asia increased by 3.00% in incidence from 2010 to 2021, while overall prevalence decreased by 1.00%, yet the age-standardized prevalence rate remains above the global rate (91,570 per 100,000 population). Incidences of cardiovascular and respiratory diseases declined by 3.00% and 13.00%, respectively, whereas diabetes and cancer rose by 21.00% and 13.00% in South Asia. Nepal faced the highest environmental impact (23.4% of DALYs), Bangladesh the greatest metabolic impact (25.62%), and India the highest from behavioural factors (23.95%). Population growth and aging were primary drivers of changes in deaths and DALYs across the region.

Conclusion: This finding emphasizes the need for targeted public health interventions addressing environmental, metabolic, and behavioral risks for NCDs in South Asia, alongside strategies to support healthy aging and effective disease management across diverse demographic groups.

南亚非传染性疾病负担:分解分析。
背景:本研究考察了南亚地区与非传染性疾病(ncd)相关的发病率、患病率、死亡率和伤残调整生命年(DALYs),探讨了环境、代谢和行为风险因素,并探讨了人口增长、老龄化和死亡率驱动的死亡和伤残调整生命年的变化。方法:使用2021年全球疾病负担(GBD)研究的数据,我们估计了2010年至2021年四种主要非传染性疾病(心血管疾病、癌症、糖尿病和慢性呼吸系统疾病)的年龄标准化发病率、患病率、死亡和DALYs。对所有非传染性疾病进行了特定性别和年龄的估计,采用95%的不确定区间,并采用分解分析来估计非传染性疾病导致的死亡和伤残调整生命年的变化。研究结果:从2010年到2021年,南亚非传染性疾病的发病率增加了3.00%,而总体患病率下降了1.00%,但年龄标准化患病率仍高于全球水平(每10万人中有91570人)。南亚心血管和呼吸系统疾病的发病率分别下降了3.00%和13.00%,而糖尿病和癌症的发病率分别上升了21.00%和13.00%。尼泊尔面临的环境影响最大(占DALYs的23.4%),孟加拉国的代谢影响最大(25.62%),印度的行为因素影响最大(23.95%)。人口增长和老龄化是整个区域死亡和伤残调整生命年变化的主要驱动因素。结论:这一发现强调需要有针对性的公共卫生干预措施来解决南亚非传染性疾病的环境、代谢和行为风险,以及支持不同人口群体健康老龄化和有效疾病管理的战略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Health, Population, and Nutrition
Journal of Health, Population, and Nutrition 医学-公共卫生、环境卫生与职业卫生
CiteScore
2.20
自引率
0.00%
发文量
49
审稿时长
6 months
期刊介绍: Journal of Health, Population and Nutrition brings together research on all aspects of issues related to population, nutrition and health. The journal publishes articles across a broad range of topics including global health, maternal and child health, nutrition, common illnesses and determinants of population health.
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