Carlos Ramirez Mañas, Raquel Alarcón Rodríguez, José Puentes Sánchez, Carmen María Pardo González, Jéssica García Gonzalez, María Del Mar Requena Mullor
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引用次数: 0
Abstract
Objective: Diabetic foot ulcers (DFUs) are at significant risk of becoming infected, with an associated elevated risk of amputation. Choosing an appropriate treatment would help prevent infection, improve healing and patients' quality of life, as well as reduce healthcare costs. The aim of this study was to assess the efficacy of a dialkylcarbamoyl chloride (DACC)-coated wound dressing to reduce bacterial load in the treatment of infected diabetic foot ulcers with signs of biofilm.
Method: In this prospective, descriptive observational study, patients with infected DFUs were treated with a DACC-coated wound dressing, and were followed until complete healing was achieved. Levels of bacterial load and the presence of biofilm were also assessed.
Results: The patients consisted of 42 males and 19 females, with a mean age of 54.4 years. All wounds exhibited complete wound closure upon treatment with the DACC-coated wound dressing, with an average time to heal of 71.8 days. A total of 53 patients had received systemic antibiotic treatment prior to study enrolment, and the number of patients requiring antibiotic treatment reduced to 20 during the study. The level of bacterial load (including biofilm) was reduced, leading to wound progression in a proportion of wounds.
Conclusion: The findings of this study revealed that treatment with a non-medicated antimicrobial wound dressing was an appropriate dressing choice to reduce microbial load and aid promotion of healing in infected DFUs with the presence of biofilm.
期刊介绍：
Journal of Wound Care (JWC) is the definitive wound-care journal and the leading source of up-to-date research and clinical information on everything related to tissue viability. The journal was first launched in 1992 and aimed at catering to the needs of the multidisciplinary team. Published monthly, the journal’s international audience includes nurses, doctors and researchers specialising in wound management and tissue viability, as well as generalists wishing to enhance their practice.
In addition to cutting edge and state-of-the-art research and practice articles, JWC also covers topics related to wound-care management, education and novel therapies, as well as JWC cases supplements, a supplement dedicated solely to case reports and case series in wound care. All articles are rigorously peer-reviewed by a panel of international experts, comprised of clinicians, nurses and researchers.
Specifically, JWC publishes:
High quality evidence on all aspects of wound care, including leg ulcers, pressure ulcers, the diabetic foot, burns, surgical wounds, wound infection and more
The latest developments and innovations in wound care through both preclinical and preliminary clinical trials of potential new treatments worldwide
In-depth prospective studies of new treatment applications, as well as high-level research evidence on existing treatments
Clinical case studies providing information on how to deal with complex wounds
Comprehensive literature reviews on current concepts and practice, including cost-effectiveness
Updates on the activities of wound care societies around the world.
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