A Collagen-Elastin Regenerative Dermal Matrix May Generate Unfavorable Results in Head and Neck Postburn Scar Reconstruction: A Case Series.

IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL
Bogdan Nitescu, Andrei Dumitrescu, Florin Radu Stanescu, Diana Cintacioiu, Gratiana Lates, Sorin Viorel Parasca
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Abstract

Background and Objectives: Dermal matrices have brought solutions for many problems, mainly in the treatment of burns and burn scar revisions. The objective of this study was to draw attention to the limits of a collagen-elastin dermal matrix (MatriDerm®) in its 1 mm variant for the treatment of burn scars on the face and neck. Materials and Methods: A case series of four patients (three women and one man) with burn scars of the face (one case) and of the neck (three cases) treated with collagen-elastin matrices is presented. In all cases, the excision or release of the scars was performed, and the defects were covered with MatriDerm® and thin split-thickness skin grafts in the same operative time. Results: In all cases, the graft take was very good but was followed by the important contraction of the graft to such an extent that the results were found to be poor by both the surgeons and the patients. The surface of the new scar was irregular, and the elasticity was low. The article points out some probable causes and draws attention to the need for more objective studies regarding the use of this dermal matrix in burn scars of the head and neck. Conclusions: This collagen-elastin 1 mm dermal matrix should be used with caution for the surgical treatment of burn scars of the head and neck area, and its indication should be carefully weighted.

胶原-弹性蛋白再生真皮基质可能对头颈部烧伤后瘢痕重建产生不利影响:一个病例系列。
背景与目的:真皮基质已经解决了许多问题,主要是烧伤的治疗和烧伤疤痕的修复。本研究的目的是引起人们对胶原-弹性蛋白真皮基质(MatriDerm®)1毫米变体用于治疗面部和颈部烧伤疤痕的局限性的关注。材料与方法:本文介绍了用胶原-弹性蛋白基质治疗面部(1例)和颈部(3例)烧伤疤痕的4例患者(3女1男)的病例系列。所有病例均切除或释放疤痕,并在相同的手术时间内用MatriDerm®和薄片状皮肤移植物覆盖缺损。结果:在所有病例中,移植物的效果都很好,但随之而来的是移植物的重要收缩,以至于外科医生和患者都认为结果很差。新瘢痕表面不规则,弹性较低。文章指出了一些可能的原因,并提请注意,需要更多的客观研究关于使用这种真皮基质烧伤疤痕的头颈部。结论:该胶原-弹性蛋白1 mm真皮基质在头颈部烧伤疤痕的手术治疗中应谨慎使用,并应仔细权衡其适应证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medicina-Lithuania
Medicina-Lithuania 医学-医学:内科
CiteScore
3.30
自引率
3.80%
发文量
1578
审稿时长
25.04 days
期刊介绍: The journal’s main focus is on reviews as well as clinical and experimental investigations. The journal aims to advance knowledge related to problems in medicine in developing countries as well as developed economies, to disseminate research on global health, and to promote and foster prevention and treatment of diseases worldwide. MEDICINA publications cater to clinicians, diagnosticians and researchers, and serve as a forum to discuss the current status of health-related matters and their impact on a global and local scale.
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