Bogdan Nitescu, Andrei Dumitrescu, Florin Radu Stanescu, Diana Cintacioiu, Gratiana Lates, Sorin Viorel Parasca
{"title":"A Collagen-Elastin Regenerative Dermal Matrix May Generate Unfavorable Results in Head and Neck Postburn Scar Reconstruction: A Case Series.","authors":"Bogdan Nitescu, Andrei Dumitrescu, Florin Radu Stanescu, Diana Cintacioiu, Gratiana Lates, Sorin Viorel Parasca","doi":"10.3390/medicina61040744","DOIUrl":null,"url":null,"abstract":"<p><p><i>Background and Objectives:</i> Dermal matrices have brought solutions for many problems, mainly in the treatment of burns and burn scar revisions. The objective of this study was to draw attention to the limits of a collagen-elastin dermal matrix (MatriDerm<sup>®</sup>) in its 1 mm variant for the treatment of burn scars on the face and neck. <i>Materials and Methods:</i> A case series of four patients (three women and one man) with burn scars of the face (one case) and of the neck (three cases) treated with collagen-elastin matrices is presented. In all cases, the excision or release of the scars was performed, and the defects were covered with MatriDerm<sup>®</sup> and thin split-thickness skin grafts in the same operative time. <i>Results:</i> In all cases, the graft take was very good but was followed by the important contraction of the graft to such an extent that the results were found to be poor by both the surgeons and the patients. The surface of the new scar was irregular, and the elasticity was low. The article points out some probable causes and draws attention to the need for more objective studies regarding the use of this dermal matrix in burn scars of the head and neck. <i>Conclusions:</i> This collagen-elastin 1 mm dermal matrix should be used with caution for the surgical treatment of burn scars of the head and neck area, and its indication should be carefully weighted.</p>","PeriodicalId":49830,"journal":{"name":"Medicina-Lithuania","volume":"61 4","pages":""},"PeriodicalIF":2.4000,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12028597/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina-Lithuania","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/medicina61040744","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background and Objectives: Dermal matrices have brought solutions for many problems, mainly in the treatment of burns and burn scar revisions. The objective of this study was to draw attention to the limits of a collagen-elastin dermal matrix (MatriDerm®) in its 1 mm variant for the treatment of burn scars on the face and neck. Materials and Methods: A case series of four patients (three women and one man) with burn scars of the face (one case) and of the neck (three cases) treated with collagen-elastin matrices is presented. In all cases, the excision or release of the scars was performed, and the defects were covered with MatriDerm® and thin split-thickness skin grafts in the same operative time. Results: In all cases, the graft take was very good but was followed by the important contraction of the graft to such an extent that the results were found to be poor by both the surgeons and the patients. The surface of the new scar was irregular, and the elasticity was low. The article points out some probable causes and draws attention to the need for more objective studies regarding the use of this dermal matrix in burn scars of the head and neck. Conclusions: This collagen-elastin 1 mm dermal matrix should be used with caution for the surgical treatment of burn scars of the head and neck area, and its indication should be carefully weighted.
期刊介绍:
The journal’s main focus is on reviews as well as clinical and experimental investigations. The journal aims to advance knowledge related to problems in medicine in developing countries as well as developed economies, to disseminate research on global health, and to promote and foster prevention and treatment of diseases worldwide. MEDICINA publications cater to clinicians, diagnosticians and researchers, and serve as a forum to discuss the current status of health-related matters and their impact on a global and local scale.