Sheetal S Choudhari, Sangeeta R Patankar, Vibhuti S Mhatre, Anish Gupta
{"title":"Verruciform xanthoma: A case report and a review of recurrent cases.","authors":"Sheetal S Choudhari, Sangeeta R Patankar, Vibhuti S Mhatre, Anish Gupta","doi":"10.4103/jomfp.jomfp_177_24","DOIUrl":null,"url":null,"abstract":"<p><p>Oral verruciform xanthoma (VX) is an infrequently encountered benign lesion in the oral cavity. We report an unusual case of VX on the left buccal mucosa presented as a red and white exophytic mass with a greyish white diffuse patch associated with it. A differential diagnosis of papilloma, verrucous carcinoma, and squamous cell carcinoma associated with leukoplakia was listed. Histopathological findings were suggestive of VX due to the presence of characteristic foam cells in the connective tissue papillae. Immunohistochemical analysis with CD68 showed strong positive immunoreactivity revealing expression of foam cells. After the excisional biopsy, the patient was followed up for the next 6 months with no recurrence. Follow-up is very essential in such a case as the exophytic lesion was associated with a potentially malignant disorder. A short review of reported recurrent cases of verruciform xanthoma is also discussed.</p>","PeriodicalId":38846,"journal":{"name":"Journal of Oral and Maxillofacial Pathology","volume":"29 1","pages":"152-157"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002571/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oral and Maxillofacial Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jomfp.jomfp_177_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/28 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Oral verruciform xanthoma (VX) is an infrequently encountered benign lesion in the oral cavity. We report an unusual case of VX on the left buccal mucosa presented as a red and white exophytic mass with a greyish white diffuse patch associated with it. A differential diagnosis of papilloma, verrucous carcinoma, and squamous cell carcinoma associated with leukoplakia was listed. Histopathological findings were suggestive of VX due to the presence of characteristic foam cells in the connective tissue papillae. Immunohistochemical analysis with CD68 showed strong positive immunoreactivity revealing expression of foam cells. After the excisional biopsy, the patient was followed up for the next 6 months with no recurrence. Follow-up is very essential in such a case as the exophytic lesion was associated with a potentially malignant disorder. A short review of reported recurrent cases of verruciform xanthoma is also discussed.
期刊介绍：
The journal of Oral and Maxillofacial Pathology [ISSN:print-(0973-029X, online-1998-393X)] is a tri-annual journal published on behalf of “The Indian Association of Oral and Maxillofacial Pathologists” (IAOMP). The publication of JOMFP was started in the year 1993. The journal publishes papers on a wide spectrum of topics associated with the scope of Oral and Maxillofacial Pathology, also, ensuring scientific merit and quality. It is a comprehensive reading material for the professionals who want to upgrade their diagnostic skills in Oral Diseases; allows exposure to newer topics and methods of research in the Oral-facial Tissues and Pathology. New features allow an open minded thinking and approach to various pathologies. It also encourages authors to showcase quality work done by them and to compile relevant cases which are diagnostically challenging. The Journal takes pride in maintaining the quality of articles and photomicrographs.
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