Assessing trachoma elimination progress in districts with persistent trachoma, Western Province, Zambia.

IF 2.3 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Health Pub Date : 2025-04-26 DOI:10.1093/inthealth/ihaf041

Consity Mwale, Chileshe Mboni, Ngonda Saasa, Chummy S Sikasunge, Chisanga Chelu, Tina Chisenga, Lubasi Sundano, Namasiku Siyumbwa Kunda, Phyllis M Moonga, Kaluba Lombe, Tabonga Naluonde, Sarah Boyd, Ana Bakhtiari, Cristina Jimenez, Emma M Harding-Esch, Michael Dejene, Freddie Masaninga, Nathan N Bakyaita, Davison Kwendakwema, Anthony W Solomon, Kangwa I M Muma

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引用次数: 0

Abstract

Background: Trachoma is a public health problem in Zambia. We aimed to estimate the prevalence of trachomatous inflammation-follicular (TF) in 1-9-y-olds and of trachomatous trichiasis (TT) in ≥15-y-olds after the implementation of trachoma elimination interventions to determine if the trachoma elimination thresholds had been achieved: <5% for TF in 1-9-y-olds and <0.2% TT for ≥15-y-olds.

Methods: Two rounds of impact prevalence surveys in two evaluation units (EUs) comprising four districts of Western Province were conducted; the first in 2018, the second in 2023. All individuals aged ≥1 year from 30 households of 24 clusters in each EU were examined for trachoma. Data were captured electronically.

Results: In 2018, TF prevalence in 1-9-y-olds was 13.9% in Kalabo/Sikongo and 17.9% in Shang'ombo/Sioma. Following further interventions, TF prevalence among 1-9-y-olds in 2023 was 7.7% and 12.5%, respectively. TT prevalences in ≥15-y-olds were 0.10% and 0.79% in 2018, and 0.4% and 0.2% in 2023, respectively.

Conclusions: These EUs did not attain trachoma elimination thresholds as a public health problem. They fulfilled the WHO definition for persistent trachoma. Therefore, they warrant further investigation, including collection of Chlamydia trachomatis infection data, to inform future programmatic decision-making. Further TT surgical services are also needed.

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评估赞比亚西部省持续性沙眼地区消除沙眼的进展。

背景：沙眼是赞比亚的一个公共卫生问题。我们的目的是在实施沙眼消除干预措施后，估计1-9岁儿童的沙眼炎症-滤泡（TF）患病率和≥15岁儿童的沙眼睫（TT）患病率，以确定是否达到了沙眼消除阈值：方法：在西部省四个地区的两个评估单位（EUs）进行了两轮影响患病率调查；第一次在2018年，第二次在2023年。来自每个欧盟24个群集的30个家庭的所有年龄≥1岁的个体进行了沙眼检查。数据以电子方式捕获。结果：2018年Kalabo/Sikongo地区1-9岁青少年TF患病率为13.9%,Shang’ombo/Sioma地区为17.9%。经过进一步干预，2023年1-9岁儿童的TF患病率分别为7.7%和12.5%。2018年，≥15岁青少年的TT患病率分别为0.10%和0.79%，2023年分别为0.4%和0.2%。结论：这些EUs没有达到作为公共卫生问题的沙眼消除阈值。他们符合世卫组织对持续性沙眼的定义。因此，它们值得进一步调查，包括收集沙眼衣原体感染数据，以便为未来的规划决策提供信息。还需要进一步的TT手术服务。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： International Health is an official journal of the Royal Society of Tropical Medicine and Hygiene. It publishes original, peer-reviewed articles and reviews on all aspects of global health including the social and economic aspects of communicable and non-communicable diseases, health systems research, policy and implementation, and the evaluation of disease control programmes and healthcare delivery solutions. It aims to stimulate scientific and policy debate and provide a forum for analysis and opinion sharing for individuals and organisations engaged in all areas of global health.