The Correlation Between Fetal Wellbeing and Umbilical Doppler Parameters in Pregnant Women with Gestational Hypertension.

IF 2.5 4区医学 Q2 OBSTETRICS & GYNECOLOGY

International Journal of Women's Health Pub Date : 2025-04-09 eCollection Date: 2025-01-01 DOI:10.2147/IJWH.S514427

Hualan Lin, Meifang Shen, Dongbei Li, Qiuxia Sun, Liubing Lan

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引用次数: 0

Abstract

Objective: To investigate the role of umbilical cord blood flow parameters in evaluating intrauterine fetal hypoxia and fetal growth restriction in pregnant women with gestational hypertension.

Methods: One hundred and nine patients with gestational hypertension admitted from January 2020 to December 2023 were enrolled in this study. The peak systolic velocity/end diastolic velocity (S/D), pulse index (PI) and resistance index (RI) of cord blood were measured by ultrasound. According to the S/D, 109 cases were divided into 62 cases in the control group (S/D < 3) and 47 cases in the observation group (S/D ≥ 3), and the prognosis of pregnant women and fetuses in the two groups were compared. The ROC curves were used to analyze the effects of different parameters of umbilical blood flow on intrauterine fetal hypoxia and fetal growth restriction in pregnant women with gestational hypertension.

Results: The incidence of intrauterine fetal hypoxia, fetal growth restriction, cesarean section, and unresponsive type of non-irritation test was decreased in the control group compared with the observation group (P < 0.05). However, there was no statistical difference in the incidence of neonatal asphyxia between the two groups (P > 0.05). ROC curve analysis showed that cord blood flow RI of pregnant women with gestational hypertension had the highest sensitivity and AUC in predicting intrauterine fetal hypoxia and growth restriction, and PI had the highest specificity in predicting intrauterine fetal growth restriction. The specificity of S/D, PI and RI in predicting intrauterine hypoxia was consistent (all 80%).

Conclusion: The different parameters of umbilical blood flow in hypertensive pregnant women during pregnancy provide a good assessment of intrauterine fetal condition and can be used as clinical indicators to predict poor prognosis of intrauterine fetal hypoxia and fetal growth restriction.

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妊娠期高血压孕妇胎儿健康与脐多普勒参数的关系。

目的：探讨脐带血流量参数在评价妊娠期高血压孕妇宫内胎儿缺氧和胎儿生长受限中的作用。方法：选取2020年1月至2023年12月住院的109例妊娠期高血压患者作为研究对象。超声检测脐带血收缩峰速度/舒张末速度（S/D）、脉搏指数（PI）和阻力指数（RI）。根据S/D将109例患者分为对照组62例（S/D < 3）和观察组47例（S/D≥3），比较两组孕妇及胎儿的预后。采用ROC曲线分析不同脐血流量参数对妊娠期高血压孕妇宫内胎儿缺氧和胎儿生长受限的影响。结果：对照组宫内胎儿缺氧、胎儿生长受限、剖宫产、无刺激试验无反应型发生率均低于观察组（P < 0.05）。两组新生儿窒息发生率比较，差异无统计学意义（P < 0.05）。ROC曲线分析显示，妊娠期高血压孕妇脐带血流量RI预测宫内胎儿缺氧和生长受限的敏感性和AUC最高，PI预测宫内胎儿生长受限的特异性最高。S/D、PI和RI预测宫内缺氧的特异性一致（均为80%）。结论：妊娠期高血压孕妇脐血流量的不同参数能较好地评估宫内胎儿状况，可作为预测宫内胎儿缺氧和胎儿生长受限预后不良的临床指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Women's Health OBSTETRICS & GYNECOLOGY-

CiteScore

3.70

自引率

0.00%

发文量

194

审稿时长

16 weeks

期刊介绍： International Journal of Women''s Health is an international, peer-reviewed, open access, online journal. Publishing original research, reports, editorials, reviews and commentaries on all aspects of women''s healthcare including gynecology, obstetrics, and breast cancer. Subject areas include: Chronic conditions including cancers of various organs specific and not specific to women Migraine, headaches, arthritis, osteoporosis Endocrine and autoimmune syndromes - asthma, multiple sclerosis, lupus, diabetes Sexual and reproductive health including fertility patterns and emerging technologies to address infertility Infectious disease with chronic sequelae including HIV/AIDS, HPV, PID, and other STDs Psychological and psychosocial conditions - depression across the life span, substance abuse, domestic violence Health maintenance among aging females - factors affecting the quality of life including physical, social and mental issues Avenues for health promotion and disease prevention across the life span Male vs female incidence comparisons for conditions that affect both genders.