Videographic and Microbiologic Evaluation of Eye Drop Bottle Contamination in Clinics: A Pilot Study.

IF 2.6 3区医学 Q2 OPHTHALMOLOGY

Journal of cataract and refractive surgery Pub Date : 2025-04-11 DOI:10.1097/j.jcrs.0000000000001670

Ishani P Majmudar, Harsha R Kaul, Anushree Aneja, Jasmyne E McCoy, Sahana Aggarwal, Nathan P Gill, Justin Mussman, Robert O Baker, David J Palmer, Manjot K Gill

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引用次数: 0

Abstract

Background: Many multidose eyedrops in the clinic and operating room are discarded after single use due to cross-contamination concerns. This practice contributes to significant hospital costs, drug shortages, and unnecessary greenhouse gas emissions.

Methods: 9-week, prospective, observational study of 97 patients.

Objective: To validate the safety of multidose eyedrops in the ophthalmology clinic by ASORN-trained technicians using a videographic and microbiological analysis. Secondly, to determine optimal culturing conditions to prevent environmental contamination.

Results: During eyedrop administration, no videos demonstrated bottle-to-patient contact. 12/96 (12.5%) plates demonstrated growth, likely due to environmental contamination. Mass spectrometry revealed non-pathogenic and common species for 8 identifiable growths. Environmental contamination is minimized by use of a biosafety cabinet.

Conclusion: We found no clinical correlation between the use of multidose eyedrop bottles and infection on multiple patients in the ophthalmology clinic. We recommend using a biosafety cabinet to establish a national consensus for multidosing eyedrops and to improve inter-study comparisons.

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临床滴眼液瓶污染的录像和微生物学评价：一项初步研究。

背景：由于交叉污染问题，诊所和手术室的许多多剂量滴眼液在单次使用后被丢弃。这种做法造成了高昂的医院费用、药品短缺和不必要的温室气体排放。方法：对97例患者进行为期9周的前瞻性观察性研究。目的：通过影像和微生物学分析，验证asorn培训技师在眼科临床使用多剂量滴眼液的安全性。其次，确定最佳培养条件，防止环境污染。结果：在滴眼液使用期间，没有视频显示瓶子与患者接触。12/96（12.5%）板显示生长，可能是由于环境污染。质谱分析显示非致病性和常见的8种可识别的生长。使用生物安全柜可将环境污染降至最低。结论：我们发现眼科门诊多剂量滴眼液瓶的使用与多例患者感染无临床相关性。我们建议使用生物安全柜来建立多剂量眼药水的全国共识，并改善研究间的比较。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

$Journal of cataract and refractive surgery$

Journal of cataract and refractive surgery 医学-外科

CiteScore

5.60

自引率

14.30%

发文量

259

审稿时长

8.5 weeks

期刊介绍： The Journal of Cataract & Refractive Surgery (JCRS), a preeminent peer-reviewed monthly ophthalmology publication, is the official journal of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS). JCRS publishes high quality articles on all aspects of anterior segment surgery. In addition to original clinical studies, the journal features a consultation section, practical techniques, important cases, and reviews as well as basic science articles.