Thatyana Ribeiro Medeiros, Camila Barros Melgaço da Silva, Flávia Nunes Benicio de Souza, Hannah Schmidel Kautsky, Luana Martins de Oliveira, Luana Martins de Toledo, Alan Araújo Vieira
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引用次数: 0
Abstract
Objective: Bioelectrical impedance analysis is a method used to assess body composition; a noninvasive test performed using an easy-to-handle portable device used in clinical practice. However, nonstandard methods in neonates hinder external validation and reliability. Currently, bioimpedance analysis is performed in newborns with electrodes positioned on the right side of the body; however, the use of medical devices, including vascular access, can prevent its use.
Methods: An uncontrolled before-after clinical trial comparing resistance and reactance measurements by bioelectrical impedance analysis on both sides was conducted. Measurements were performed immediately after the randomization of the initial measurement side. The sample size was calculated by considering a 10% deviation from the mean resistance and reactance values of previous studies with alpha and beta errors of 10% and 20%, respectively. Binary linear regression was used to quantify the correlation.
Results: A significant difference was observed between resistance (672.88 ± 136.30 vs. 649.22 ± 119.59) and reactance (46.34 ± 17.99 vs. 44.439 ± 19.42) values measured on the right and left sides, respectively. However, when measured on both sides of the body, resistance and reactance values showed a good correlation (0.98 for both models, p < 0.001). Positioning the electrodes on the left side significantly affected the resistance and reactance values measured by bioelectrical impedance analysis compared with those on the right side.
Conclusion: Electrodes positioned on opposite sides of the body generated different resistance and reactance values, implying the need to use the right side exclusively for standard positioning. This restriction can create difficulties for the routine use of this technique in newborns.
目的：生物电阻抗分析是一种评价人体成分的方法；在临床实践中使用易于操作的便携式设备进行的一种无创测试。然而，新生儿的非标准方法阻碍了外部验证和可靠性。目前，生物阻抗分析是在新生儿中进行的，电极位于身体的右侧；然而，医疗设备的使用，包括血管通道，可以阻止其使用。方法：采用非对照临床试验，比较双侧生物阻抗法测定的电阻和电抗。在初始测量侧随机化后立即进行测量。样本量的计算考虑了与以往研究的电阻和电抗平均值有10%的偏差，alpha和beta误差分别为10%和20%。采用二元线性回归对相关性进行量化。结果：左右两侧电阻值（672.88±136.30 vs. 649.22±119.59）和电抗（46.34±17.99 vs. 44.439±19.42）差异有统计学意义。然而，当在身体两侧测量时，电阻和电抗值显示出良好的相关性（两个模型均为0.98,p < 0.001）。与右侧电极相比，左侧电极对生物电阻抗分析测量的电阻和电抗值有显著影响。结论：放置在身体两侧的电极产生不同的电阻和电抗值，意味着需要仅使用右侧进行标准定位。这一限制可能给新生儿常规使用该技术带来困难。
期刊介绍：
Jornal de Pediatria is a bimonthly publication of the Brazilian Society of Pediatrics (Sociedade Brasileira de Pediatria, SBP). It has been published without interruption since 1934. Jornal de Pediatria publishes original articles and review articles covering various areas in the field of pediatrics. By publishing relevant scientific contributions, Jornal de Pediatria aims at improving the standards of pediatrics and of the healthcare provided for children and adolescents in general, as well to foster debate about health.
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