Adherence to the Korean National Code Against Cancer and mortality: a prospective cohort study from the Health Examinees-Gem study.

IF 2.2 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Epidemiology and Health Pub Date : 2025-05-09 DOI:10.4178/epih.e2025026

Jeeyoo Lee, Aesun Shin, Woo-Kyoung Shin, Ji-Yeob Choi, Daehee Kang

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引用次数: 0

Abstract

Objectives: The Korean National Code Against Cancer was released in 2006. These guidelines aimed to promote a healthy lifestyle to prevent cancer risk through 10 recommendations. The objective of this study was to investigate the associations between adherence to the Korean National Code Against Cancer and the risk of all-cause, cancer, and cardiovascular disease (CVD) mortality among Koreans.

Methods: This prospective cohort study included 109,160 Korean adults aged 40 to 69 years, recruited from 2004 to 2013 in the population-based Health Examinees-Gem Study (HEXA-G). The adherence total score was calculated based on 6 items from the Korean National Code Against Cancer: smoking, consuming vegetables and fruits, limiting salty foods, restricting alcohol intake, engaging in physical activity, and maintaining a healthy weight. Hazard ratios (HRs) and 95% confidence intervals (CIs) for the associations of adherence scores with mortality risk were estimated using a Cox proportional hazards regression model.

Results: During a mean follow-up period of 12.0 years, 3,799 deaths were recorded. According to the multivariable-adjusted model, men in the highest tertile of adherence scores had a lower risk of all-cause, cancer, and CVD mortality compared to those in the lowest tertile (all-cause: HR=0.67, 95% CI=0.60-0.74; cancer: HR=0.63, 95% CI=0.54-0.74; CVD: HR=0.56, 95% CI=0.43-0.73). A similar association was observed among women for all-cause and CVD mortality (all-cause: HR=0.85, 95% CI=0.76-0.96; CVD: HR=0.70, 95% CI=0.51-0.97).

Conclusion: Adherence to the Korean National Code Against Cancer was associated with a reduced risk of all-cause, cancer, and CVD mortality.

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遵守韩国国家癌症法典和死亡率：来自健康考生gem研究的前瞻性队列研究

目标：2006年颁布了《韩国国家抗癌法典》。这些指南旨在通过10条建议促进健康的生活方式以预防癌症风险。本研究的目的是调查韩国人遵守《韩国国家癌症法典》与全因、癌症和心血管疾病（CVD）死亡风险之间的关系。方法：这项前瞻性队列研究包括109,160名年龄在40至69岁之间的韩国成年人，他们于2004年至2013年在以人群为基础的健康体检者-宝石研究（HEXA-G）中招募。依从性总分是根据《大韩民国抗癌守则》中吸烟、食用蔬菜和水果、限制含盐食品、限制饮酒、参加体育锻炼、保持健康体重等6个项目计算的。使用Cox比例风险回归模型估计依从性评分与死亡风险相关性的风险比（hr）和95%置信区间（CIs）。结果：在平均12.0年的随访期间，记录了3799例死亡。根据多变量调整模型，与最低分位数的男性相比，依从性得分最高的男性的全因、癌症和心血管疾病死亡风险较低(全因：HR=0.67, 95% CI=0.60-0.74；癌症：HR=0.63, 95% CI=0.54-0.74；Cvd: hr =0.56, 95% ci =0.43-0.73)。在女性全因死亡率和心血管疾病死亡率中也观察到类似的关联(全因死亡率：HR=0.85, 95% CI=0.76-0.96；Cvd: hr =0.70, 95% ci =0.51-0.97)。结论：遵守韩国国家抗癌法典与全因、癌症和心血管疾病死亡率降低相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Epidemiology and Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

6.30

自引率

2.60%

发文量

106

审稿时长

4 weeks

期刊介绍： Epidemiology and Health (epiH) is an electronic journal publishing papers in all areas of epidemiology and public health. It is indexed on PubMed Central and the scope is wide-ranging: including descriptive, analytical and molecular epidemiology; primary preventive measures; screening approaches and secondary prevention; clinical epidemiology; and all aspects of communicable and non-communicable diseases prevention. The epiH publishes original research, and also welcomes review articles and meta-analyses, cohort profiles and data profiles, epidemic and case investigations, descriptions and applications of new methods, and discussions of research theory or public health policy. We give special consideration to papers from developing countries.