The effect of preoperative body weight loss on 5-year bariatric surgery outcomes.

IF 3.8 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

International Journal of Obesity Pub Date : 2025-05-05 DOI:10.1038/s41366-025-01794-6

L Flores, A Andreu, R Olbeyra, S Cañizares, M Claro, J Ríos, J Molero, A Jiménez, J Vidal

{"title":"The effect of preoperative body weight loss on 5-year bariatric surgery outcomes.","authors":"L Flores, A Andreu, R Olbeyra, S Cañizares, M Claro, J Ríos, J Molero, A Jiménez, J Vidal","doi":"10.1038/s41366-025-01794-6","DOIUrl":null,"url":null,"abstract":"Objectives: This study aimed to evaluate the effect of preoperative total body weight loss (TBWL) following a structured 6-month lifestyle change programme (LCP) on the level of TBWL at 12 months and its maintenance at 60 months post bariatric surgery (BS), as well as its impact on operation time, hospital stay, surgical complications and obesity-associated pathology remission.Methods: This retrospective, single-centre study analysed patients undergoing primary BS between 2013 and 2014. Outcomes were compared between patients participating in the LCP (LCP group) and those receiving standard preoperative education (Control group: CG). Data collected included anthropometric measurements, obesity-related pathologies, surgical complications, and weight-related outcomes.Results: Among 340 BS procedures performed, 165 patients met the inclusion criteria; 59 in the LCP group and 106 in the CG. The mean age was 47 ( ± 11.6) years in the LCP group and 45 ( ± 11.1) years in the CG with no significant differences in baseline clinical characteristics. At surgery, the LCP group showed significant weight reduction (-5.9 kg vs. -0.72 kg in controls, p = 0.008) and their BMI was significantly lower (46.55 vs. 49.47 kg/m², p = 0.002). Postoperatively, weight-related outcomes [BMI and TBWL] were better in the LCP group at 1 and 5 years. Additionally, patients achieving a preoperative TBWL > 5% demonstrated a significantly lower weight and BMI, along with a higher postoperative TBWL. Surgical complications were minimal, with no significant differences in 30-day complication rates. We did not observe a greater resolution of comorbidities in patients who participated in the LCP or those who achieved a preoperative TBWL ≥ 5%.Conclusions: While current evidence suggests that preoperative TBWL provides short-term benefits, our data suggest this may also be the case for TBWL in the long-term. Further research is needed to fully elucidate the role of preoperative TBWL in comorbidity resolution in BS patients.","PeriodicalId":14183,"journal":{"name":"International Journal of Obesity","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Obesity","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1038/s41366-025-01794-6","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives: This study aimed to evaluate the effect of preoperative total body weight loss (TBWL) following a structured 6-month lifestyle change programme (LCP) on the level of TBWL at 12 months and its maintenance at 60 months post bariatric surgery (BS), as well as its impact on operation time, hospital stay, surgical complications and obesity-associated pathology remission.

Methods: This retrospective, single-centre study analysed patients undergoing primary BS between 2013 and 2014. Outcomes were compared between patients participating in the LCP (LCP group) and those receiving standard preoperative education (Control group: CG). Data collected included anthropometric measurements, obesity-related pathologies, surgical complications, and weight-related outcomes.

Results: Among 340 BS procedures performed, 165 patients met the inclusion criteria; 59 in the LCP group and 106 in the CG. The mean age was 47 ( ± 11.6) years in the LCP group and 45 ( ± 11.1) years in the CG with no significant differences in baseline clinical characteristics. At surgery, the LCP group showed significant weight reduction (-5.9 kg vs. -0.72 kg in controls, p = 0.008) and their BMI was significantly lower (46.55 vs. 49.47 kg/m², p = 0.002). Postoperatively, weight-related outcomes [BMI and TBWL] were better in the LCP group at 1 and 5 years. Additionally, patients achieving a preoperative TBWL > 5% demonstrated a significantly lower weight and BMI, along with a higher postoperative TBWL. Surgical complications were minimal, with no significant differences in 30-day complication rates. We did not observe a greater resolution of comorbidities in patients who participated in the LCP or those who achieved a preoperative TBWL ≥ 5%.

Conclusions: While current evidence suggests that preoperative TBWL provides short-term benefits, our data suggest this may also be the case for TBWL in the long-term. Further research is needed to fully elucidate the role of preoperative TBWL in comorbidity resolution in BS patients.

查看原文本刊更多论文

术前体重减轻对5年减肥手术结果的影响。

目的：本研究旨在评估结构化6个月生活方式改变计划（LCP）后术前总体重减轻（TBWL）对减肥手术（BS）后12个月和60个月TBWL维持水平的影响，以及其对手术时间、住院时间、手术并发症和肥胖相关病理缓解的影响。方法：这项回顾性、单中心研究分析了2013年至2014年间接受原发性BS治疗的患者。比较LCP组（LCP组）和常规术前教育组（CG组）的结果。收集的数据包括人体测量、肥胖相关病理、手术并发症和体重相关结果。结果：340例BS手术中，165例患者符合纳入标准；LCP组59例，CG组106例。LCP组的平均年龄为47（±11.6）岁，CG组的平均年龄为45（±11.1）岁，基线临床特征无显著差异。手术时，LCP组体重显著减轻（-5.9 kg vs. -0.72 kg, p = 0.008）， BMI显著降低（46.55 vs. 49.47 kg/m²，p = 0.002）。术后1年和5年，LCP组的体重相关结果（BMI和TBWL）更好。此外，术前TBWL达到5%的患者表现出较低的体重和BMI，同时术后TBWL较高。手术并发症极少，30天并发症发生率无显著差异。我们没有观察到参加LCP的患者或术前TBWL≥5%的患者的合并症有更大的缓解。结论：虽然目前的证据表明术前TBWL可以提供短期益处，但我们的数据表明，TBWL的长期效果可能也是如此。需要进一步的研究来充分阐明术前TBWL在BS患者合并症解决中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of Obesity 医学-内分泌学与代谢

CiteScore

10.00

自引率

2.00%

发文量

221

审稿时长

3 months

期刊介绍： The International Journal of Obesity is a multi-disciplinary forum for research describing basic, clinical and applied studies in biochemistry, physiology, genetics and nutrition, molecular, metabolic, psychological and epidemiological aspects of obesity and related disorders. We publish a range of content types including original research articles, technical reports, reviews, correspondence and brief communications that elaborate on significant advances in the field and cover topical issues.