Prevalence and Correlates of Obsessive-Compulsive Symptoms in Adolescent Patients with Depressive and Anxiety Symptoms.

IF 1.3 Q3 PSYCHIATRY
Alpha psychiatry Pub Date : 2025-03-13 eCollection Date: 2025-04-01 DOI:10.31083/AP38997
Lingjun Chu, Nan Jiang, Xiwang Fan
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Abstract

Background: Obsessive-Compulsive Disorder (OCD) patients are often comorbid with depression and anxiety. However, limited research has explored this comorbidity from the perspective of individuals with depression and anxiety exhibiting obsessive-compulsive symptoms (OCS). This study aims to investigate the prevalence and potential associations between depression, anxiety, and OCS in the adolescent patient population.

Methods: A retrospective study was employed in this research. A total of: 327 drug-naive, first-episode adolescent patients aged 10 to 19 years, presenting both depressive and anxiety symptoms, were recruited from the Shanghai Pudong New Area Mental Health Center in China. The Chinese version of the Symptom Checklist-90 (SCL-90) was used to assess the severity of OCS. Binary logistic regression was applied to analyze the influence of depression and anxiety levels on OCS.

Results: More than half (52.3%) of the 327 adolescent participants with depressive and anxiety symptoms had severe obsessive-compulsive symptoms (OCS). Additionally, 35.9% had moderate OCS, 12.9% had mild OCS, and only 2.8% were symptom-free. The results also indicated a significant correlation between OCS and both depression (β = 0.073, Wald χ2 < 0.001, p < 0.005) and anxiety levels (β = 0.066, Wald χ2 < 0.005, p < 0.001).

Conclusions: The findings provide valuable insights into the predictive ability of depression and anxiety level in the development of OCS and OCD during adolescence, highlighting the importance of early identification and intervention. Future studies should include a larger and more diverse sample, with the incorporation of professional clinical evaluations to further verify these results.

Clinical trial registration: The study was registered at https://www.chictr.org.cn/, registration number: ChiCTR2300070007.

伴有抑郁和焦虑症状的青少年患者中强迫症的患病率及其相关因素
背景:强迫症(OCD)患者常伴有抑郁和焦虑。然而,有限的研究从表现出强迫症(OCS)的抑郁和焦虑个体的角度探讨了这种共病。本研究旨在调查青少年患者群体中抑郁、焦虑和强迫症的患病率及其潜在关联。方法:采用回顾性研究方法。研究人员从中国上海浦东新区精神卫生中心招募了327名年龄在10 - 19岁之间的首发无药青少年患者,他们同时表现出抑郁和焦虑症状。采用中文版症状量表(SCL-90)评估OCS的严重程度。采用二元logistic回归分析抑郁、焦虑水平对OCS的影响。结果:在327名有抑郁和焦虑症状的青少年参与者中,超过一半(52.3%)有严重的强迫症状(OCS)。此外,35.9%为中度OCS, 12.9%为轻度OCS,只有2.8%无症状。结果还显示,OCS与抑郁(β = 0.073, Wald χ2 < 0.001, p < 0.005)和焦虑水平(β = 0.066, Wald χ2 < 0.005, p < 0.001)均有显著相关性。结论:本研究结果为抑郁和焦虑水平对青少年OCS和OCD发展的预测能力提供了有价值的见解,强调了早期识别和干预的重要性。未来的研究应该包括更大、更多样化的样本,并结合专业的临床评估来进一步验证这些结果。临床试验注册:本研究注册于https://www.chictr.org.cn/,注册号:ChiCTR2300070007。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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