Evaluation of optical coherence tomography changes in amblyopia.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY

Indian Journal of Ophthalmology Pub Date : 2025-05-01 Epub Date: 2025-04-24 DOI:10.4103/IJO.IJO_3040_23

Jawahar L Goyal, Jigyasa Arora, Abha Gahlot, Divya Singh, Neharika Sharma, Nisha Yadav

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引用次数: 0

Abstract

Aim: To study the Central Macular Thickness (CMT) and Retinal nerve fiber layer (RNFL) thickness (RNFLT) using Optical Coherence Tomography (OCT) in cases of amblyopia.

Methods and material: The study was conducted on 30 patients of unilateral amblyopia having vision of less than 6/12 (30 amblyopic eyes and 30 fellow eyes) and age matched 30 eyes of normal controls aged between 5-30 years. Vision, Refraction and ophthalmological examination was done. OCT changes in macula and RNFL layer were evaluated in both eyes of each patient and controls. The data was statistically analyzed using SPSS version 22.

Results: Out of 30 patients 14 were anisomyopic and 16 were anisohyperopics. The mean central macular thickness among amblyopic eyes was significantly increased (238.77±3.64 µm) a.c.t fellow eyes (218.73±4.71µm). Average retinal nerve fibre layer thickness among amblyopic eyes was significantly increased (100.50±7.70 µm) a.c.t fellow eyes (95.67±6.38) (P<0.001).

Conclusions: The eyes with unilateral anisometropic amblyopia were associated with higher Central Macular Thickness (CMT) and thicker global Retinal Nerve Fibre Layer (RNFL) when compared to normal fellow eyes.

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弱视的光学相干断层扫描变化评价。

目的：利用光学相干断层扫描（OCT）研究弱视患者的中央黄斑厚度（CMT）和视网膜神经纤维层厚度（RNFLT）。方法与材料：选取视力小于6/12的单侧弱视患者30例（弱视30眼，伴视30眼），年龄匹配的正常对照30眼，年龄在5-30岁之间。行视力、屈光及眼科检查。观察两组患者及对照组双眼黄斑及RNFL层OCT变化。采用SPSS 22对数据进行统计分析。结果：30例患者中，屈光参差14例，远视16例。弱视组中央黄斑平均厚度（238.77±3.64µm）明显高于正常组（218.73±4.71µm）。弱视组的平均视网膜神经纤维层厚度（100.50±7.70µm）明显高于正常组（95.67±6.38µm）。结论：单侧屈光参差性弱视组的中央黄斑厚度（CMT）和视网膜神经纤维层（RNFL）均明显高于正常组。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Ophthalmology OPHTHALMOLOGY-

CiteScore

3.80

自引率

19.40%

发文量

1963

审稿时长

38 weeks

期刊介绍： Indian Journal of Ophthalmology covers clinical, experimental, basic science research and translational research studies related to medical, ethical and social issues in field of ophthalmology and vision science. Articles with clinical interest and implications will be given preference.