Impact of COVID-19 and factors associated with long COVID and COVID-19 vaccine uptake in people with HIV in the United Kingdom: Results from Positive Voices 2022

IF 2.8 3区医学 Q2 INFECTIOUS DISEASES

HIV Medicine Pub Date : 2025-05-01 DOI:10.1111/hiv.70026

F. Nakagawa, R. Palich, M. Kall, J. Sewell, C. Smith, C. Kelly, H. Kitt, A. Pelchen-Matthews, A. Aghaizu, A. Sparrowhawk, N. Mackie, T. Djuretic, S. Schoeman, C. Humphreys, M. Lipman, F. C. Lampe, A. J. Rodger, the PV2022 Study Group

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引用次数: 0

Abstract

Objectives

We assessed the impact of COVID-19, and the prevalence and factors associated with a history of COVID-19 infection, long COVID and incomplete COVID-19 vaccine uptake among people with HIV.

Methods

Positive Voices 2022 is a questionnaire study of people accessing HIV care in the United Kingdom (March 2022–April 2023). Logistic regression assessed factors associated with a history of COVID-19 (previous positive test), long COVID among those with a history of COVID-19 (ongoing symptoms, with COVID-19 onset >3 months previously) and incomplete COVID-19 vaccine uptake (less than three doses of vaccine), adjusted for: age; gender; ethnicity; and year of HIV diagnosis.

Results

In all, 4188 participants were included. Commonly reported negative impacts of the pandemic were on social contact (44% of participants), mental health (30%), healthcare access (26%) and financial security (25%). Overall, 2068 of 4188 (49.4%) participants had a history of COVID-19. Of these, 10.8% met criteria for long COVID, associated with female gender, unemployment, financial hardship, earlier HIV diagnosis date, diabetes diagnosis, asthma/chronic obstructive pulmonary disease diagnosis, obesity and symptoms of depression and anxiety. Overall, 95.8% reported having at least one vaccine dose, but 649 (15.7%) participants had incomplete vaccine uptake, associated with younger age, female gender, Black African ethnicity, lower education, financial hardship, unemployment, multioccupancy household, more recent HIV diagnosis, detectable HIV viral load and symptoms of depression and anxiety.

Conclusions

About half of participants had a history of COVID-19, of whom 11% had persistent symptoms (long COVID). COVID-19 vaccine uptake was high, but incomplete uptake was apparent for 16% of participants and was more common among women, younger people, Black African individuals and those with socio-economic disadvantage.

查看原文本刊更多论文

英国艾滋病毒感染者COVID-19的影响以及与长期COVID-19和COVID-19疫苗接种相关的因素：积极之声2022的结果。

目的：我们评估了COVID-19的影响，以及艾滋病毒感染者中COVID-19感染史、长期COVID和未完全接种COVID-19疫苗的患病率和相关因素。方法：Positive Voices 2022是一项针对英国艾滋病患者接受治疗的问卷调查研究（2022年3月- 2023年4月）。Logistic回归评估与以下因素相关的因素：COVID-19病史（既往阳性检测）、有COVID-19病史者的长期COVID-19（持续症状，3个月前发病）和COVID-19疫苗接种不完全（少于3剂疫苗），经以下因素调整：年龄；性别;种族的;以及艾滋病诊断年份。结果：共纳入4188名受试者。通常报告的大流行的负面影响是社会接触（44%的参与者）、心理健康（30%）、医疗保健（26%）和财务安全（25%）。总体而言，4188名参与者中有2068名（49.4%）有COVID-19病史。其中，10.8%符合长期COVID标准，与女性性别、失业、经济困难、早期艾滋病毒诊断日期、糖尿病诊断、哮喘/慢性阻塞性肺病诊断、肥胖以及抑郁和焦虑症状相关。总体而言，95.8%的参与者报告至少接种了一剂疫苗，但649名（15.7%）参与者疫苗接种不完全，这与年龄较小、女性、黑人种族、受教育程度较低、经济困难、失业、多户家庭、最近的艾滋病毒诊断、可检测的艾滋病毒载量以及抑郁和焦虑症状有关。结论：约一半的参与者有COVID-19病史，其中11%有持续症状（长COVID）。COVID-19疫苗接种率很高，但16%的参与者明显不完全接种，在妇女、年轻人、非洲黑人和社会经济弱势群体中更为常见。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HIV Medicine 医学-传染病学

CiteScore

5.10

自引率

10.00%

发文量

167

审稿时长

6-12 weeks

期刊介绍： HIV Medicine aims to provide an alternative outlet for publication of international research papers in the field of HIV Medicine, embracing clinical, pharmocological, epidemiological, ethical, preclinical and in vitro studies. In addition, the journal will commission reviews and other feature articles. It will focus on evidence-based medicine as the mainstay of successful management of HIV and AIDS. The journal is specifically aimed at researchers and clinicians with responsibility for treating HIV seropositive patients.