Healthy eating behaviors may be associated with lower risk of premature coronary artery disease: A multi-center case-control study.

IF 2.4 3区医学 Q3 ENVIRONMENTAL SCIENCES

Journal of Health, Population, and Nutrition Pub Date : 2025-04-20 DOI:10.1186/s41043-025-00869-4

Ehsan Shirvani, Noushin Mohammadifard, Mahshid Keshavarz, Fereshteh Sattar, Motahare Bateni, Ehsan Zarepur, Fahimeh Haghighatdoost, Samad Ghaffari, Nahid Salehi, Masoud Lotfizadeh, Nahid Azdaki, Ahmadreza Assareh, Mahboobeh Gholipour, Masoumeh Sadeghi, Alireza Khosravi Farsani, Nizal Sarrafzadegan

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引用次数: 0

Abstract

Background: Despite some evidence on individual eating habits in relation to cardiovascular disease, little is known about the combination of common eating habits in relation to premature coronary artery disease (PCAD).

Objective: We investigated the association between a combined eating habits score (EHS) and PCAD risk.

Methods: In this case-control study, 2022 patients with PCAD and 1063 healthy control were recruited. Women aged between 18 and 70 and men aged between 18 and 60 years were eligible. PCAD was defined as 75% or more stenosis in a single coronary artery disease or at least 50% in the left main coronary artery. Eating habits were assessed through interview and higher scores represent healthier behaviors.

Results: Participants in the fourth quartile of EHS had 22% lower risk of PCAD than those in the first quartile (95% CI: 0.61, 0.99; P = 0.024). Not adding salt at the table (OR = 0.80, 95% CI: 0.66, 0.97; P = 0.023), low-salt meals (OR = 0.75, 95% CI: 0.57, 0.99; P = 0.022), and slow eating (OR = 0.42, 95% CI: 0.24, 0.71; P < 0.001) were associated with lower risk of PCAD while more water drinking (OR = 1.56, 95% CI: 1.07, 2.27; P = 0.013), and increased meal frequency (OR = 1.85, 95% CI: 1.09, 3.13; P = 0.025) were linked with increased risk of PCAD.

Conclusion: Healthy eating behaviors score, particularly low salt intake and slow eating were associated with lower risk of PCAD. However, higher meal frequency and more water drinking were associated with increased risk of PCAD. Well-designed prospective cohort studies are required.

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健康的饮食习惯可能与降低过早冠状动脉疾病的风险有关：一项多中心病例对照研究

背景：尽管有一些证据表明个体饮食习惯与心血管疾病有关，但对于共同饮食习惯与过早冠状动脉疾病（PCAD）的关系知之甚少。目的：研究综合饮食习惯评分（EHS）与PCAD风险之间的关系。方法：在本病例对照研究中，招募了2022例PCAD患者和1063例健康对照者。年龄在18至70岁之间的妇女和18至60岁之间的男子符合资格。pad定义为单个冠状动脉病变狭窄75%或以上，或左冠状动脉主干狭窄至少50%。饮食习惯通过访谈进行评估，得分越高代表行为越健康。结果：EHS第4四分位数的参与者发生PCAD的风险比第1四分位数的参与者低22% (95% CI: 0.61, 0.99；p = 0.024)。不加盐(OR = 0.80, 95% CI: 0.66, 0.97；P = 0.023),低盐食物(OR = 0.75, 95% CI: 0.57, 0.99;P = 0.022),慢吃(OR = 0.42, 95% CI: 0.24, 0.71;结论：健康饮食行为评分，特别是低盐摄入和慢速饮食与pad风险降低相关。然而，更高的进餐频率和更多的饮水与pad的风险增加有关。需要精心设计的前瞻性队列研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Health, Population, and Nutrition 医学-公共卫生、环境卫生与职业卫生

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Journal of Health, Population and Nutrition brings together research on all aspects of issues related to population, nutrition and health. The journal publishes articles across a broad range of topics including global health, maternal and child health, nutrition, common illnesses and determinants of population health.