Gene- and cell-based therapy in cardiovascular diseases.

IF 2.6 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Cuijuan Zhang, Zhihang Du, Rui Chen, Xiaojing Liu, Dan Li
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引用次数: 0

Abstract

Cardiovascular disease (CVD) is one of the leading causes of mortality in humans, with a high prevalence. Moreover, this disease poses a serious threat to the economy. At present, treatment strategies are inadequate in both the prevention and cure of CVD. Thus, further investigations are required for the development of novel therapeutic options. Notably, gene- and cell-based therapies exhibit potential in the treatment of CVD. In the present article, gene- and cell-based therapies were reviewed in the context of CVD. The present review may provide a novel theoretical basis for improving the efficacy of CVD treatment, and demonstrate the potential of gene- and cell-based therapy in clinical practice. In addition, market analysis was carried out in the present study.

心血管疾病的基因和细胞治疗。
心血管疾病(CVD)是人类死亡的主要原因之一,发病率很高。此外,这种疾病对经济构成严重威胁。目前的治疗策略在预防和治疗心血管疾病方面都存在不足。因此,需要进一步的研究来开发新的治疗方案。值得注意的是,基因和细胞疗法在心血管疾病的治疗中显示出潜力。在本文中,基因和细胞为基础的治疗方法在心血管疾病的背景下进行了回顾。本文综述为提高心血管疾病的治疗效果提供了新的理论基础,并展示了基因和细胞治疗在临床实践中的潜力。此外,本研究还进行了市场分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.10
自引率
3.30%
发文量
367
审稿时长
1 months
期刊介绍: Journal of Cardiovascular Pharmacology is a peer reviewed, multidisciplinary journal that publishes original articles and pertinent review articles on basic and clinical aspects of cardiovascular pharmacology. The Journal encourages submission in all aspects of cardiovascular pharmacology/medicine including, but not limited to: stroke, kidney disease, lipid disorders, diabetes, systemic and pulmonary hypertension, cancer angiogenesis, neural and hormonal control of the circulation, sepsis, neurodegenerative diseases with a vascular component, cardiac and vascular remodeling, heart failure, angina, anticoagulants/antiplatelet agents, drugs/agents that affect vascular smooth muscle, and arrhythmias. Appropriate subjects include new drug development and evaluation, physiological and pharmacological bases of drug action, metabolism, drug interactions and side effects, application of drugs to gain novel insights into physiology or pathological conditions, clinical results with new and established agents, and novel methods. The focus is on pharmacology in its broadest applications, incorporating not only traditional approaches, but new approaches to the development of pharmacological agents and the prevention and treatment of cardiovascular diseases. Please note that JCVP does not publish work based on biological extracts of mixed and uncertain chemical composition or unknown concentration.
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