Effects of Blood Flow Restriction Training on Strength and Functionality in People With Knee Arthropathies: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

IF 1.2 Q3 SPORT SCIENCES
Translational sports medicine Pub Date : 2025-04-10 eCollection Date: 2025-01-01 DOI:10.1155/tsm2/3663009
Daniel C Ogrezeanu, Luís Suso-Martí, Rubén López-Bueno, Pedro Gargallo, Rodrigo Núñez-Cortés, Carlos Cruz-Montecinos, Lars Louis Andersen, José Casaña, Nicholas Rolnick, Joaquín Calatayud
{"title":"Effects of Blood Flow Restriction Training on Strength and Functionality in People With Knee Arthropathies: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.","authors":"Daniel C Ogrezeanu, Luís Suso-Martí, Rubén López-Bueno, Pedro Gargallo, Rodrigo Núñez-Cortés, Carlos Cruz-Montecinos, Lars Louis Andersen, José Casaña, Nicholas Rolnick, Joaquín Calatayud","doi":"10.1155/tsm2/3663009","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background:</b> Previous meta-analyses show contrasting findings regarding the effects of blood flow restriction training (BFRT) in different knee conditions. Furthermore, no previous dose-response analysis has been conducted to determine the dose of BFRT required for maximal strength and functionality adaptations. <b>Objective:</b> To analyze the evidence on the effects of BFRT on strength and functionality in patients with knee osteoarthritis or rheumatoid arthritis through a systematic review with dose-response meta-analysis. <b>Methods:</b> Included studies met the following criteria: participants with knee osteoarthritis or rheumatoid arthritis; low-load resistance BFRT as intervention; control group with traditional moderate or high intensity resistance training (MIRT and HIRT); include muscle strength and functionality as primary and secondary outcome measures, respectively; and only randomized controlled trials. A random-effects and a dose-response model estimated strength and functionality using estimates of the total repetitions performed. <b>Results:</b> We included five studies with a sample of 205 participants. No statistically significant differences were found between BFRT and MIRT or HIRT for strength (SMD = -0.06; 95% CI = -0.78-0.67; and <i>p</i> > 0.05) and functionality (SMD = 0.07; 95% CI = -0.23-0.37; and <i>p</i> > 0.05). We found an inverted U-shaped association between the increase in total repetitions and strength gain and between the increase in total repetitions and functional improvement. <b>Conclusions:</b> People with knee osteoarthritis or rheumatoid arthritis can use low-load BFRT for strength and functionality as a similarly effective alternative to MIRT and HIRT. A total of 2000 repetitions per BFRT program are necessary to maximize strength gains in these patients, while functional improvement requires 1800 total repetitions.</p>","PeriodicalId":75247,"journal":{"name":"Translational sports medicine","volume":"2025 ","pages":"3663009"},"PeriodicalIF":1.2000,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12006712/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Translational sports medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/tsm2/3663009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"SPORT SCIENCES","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Previous meta-analyses show contrasting findings regarding the effects of blood flow restriction training (BFRT) in different knee conditions. Furthermore, no previous dose-response analysis has been conducted to determine the dose of BFRT required for maximal strength and functionality adaptations. Objective: To analyze the evidence on the effects of BFRT on strength and functionality in patients with knee osteoarthritis or rheumatoid arthritis through a systematic review with dose-response meta-analysis. Methods: Included studies met the following criteria: participants with knee osteoarthritis or rheumatoid arthritis; low-load resistance BFRT as intervention; control group with traditional moderate or high intensity resistance training (MIRT and HIRT); include muscle strength and functionality as primary and secondary outcome measures, respectively; and only randomized controlled trials. A random-effects and a dose-response model estimated strength and functionality using estimates of the total repetitions performed. Results: We included five studies with a sample of 205 participants. No statistically significant differences were found between BFRT and MIRT or HIRT for strength (SMD = -0.06; 95% CI = -0.78-0.67; and p > 0.05) and functionality (SMD = 0.07; 95% CI = -0.23-0.37; and p > 0.05). We found an inverted U-shaped association between the increase in total repetitions and strength gain and between the increase in total repetitions and functional improvement. Conclusions: People with knee osteoarthritis or rheumatoid arthritis can use low-load BFRT for strength and functionality as a similarly effective alternative to MIRT and HIRT. A total of 2000 repetitions per BFRT program are necessary to maximize strength gains in these patients, while functional improvement requires 1800 total repetitions.

限制血流训练对膝关节病变患者力量和功能的影响:随机对照试验的系统评价和剂量反应荟萃分析。
背景:先前的荟萃分析显示了不同膝关节条件下限制血流训练(BFRT)效果的对比结果。此外,以前没有进行剂量-反应分析来确定BFRT达到最大强度和功能适应所需的剂量。目的:通过系统评价和剂量反应荟萃分析,分析BFRT对膝关节骨性关节炎或类风湿关节炎患者力量和功能影响的证据。方法:纳入的研究符合以下标准:受试者患有膝骨关节炎或类风湿关节炎;低负荷抗BFRT干预;对照组采用传统的中、高强度抗阻训练(MIRT和HIRT);分别将肌肉力量和功能作为主要和次要结果测量;而且只有随机对照试验。随机效应和剂量反应模型通过估计所进行的总重复次数来估计强度和功能。结果:我们纳入了5项研究,共205名参与者。BFRT与MIRT或HIRT在强度方面无统计学差异(SMD = -0.06;95% ci = -0.78-0.67;p < 0.05)和功能(SMD = 0.07;95% ci = -0.23-0.37;p < 0.05)。我们发现总重复次数的增加与力量增加以及总重复次数的增加与功能改善之间呈倒u型关系。结论:膝骨关节炎或类风湿关节炎患者可以使用低负荷BFRT作为MIRT和HIRT的同样有效的替代方法来增强力量和功能。在这些患者中,每次BFRT项目总共需要2000次重复才能最大限度地提高力量,而功能改善则需要1800次重复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
3.00
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信