Green-Synthesized Nanomaterials for Aflatoxin Mitigation: A Review.

Abstract

Aflatoxin contamination poses a significant challenge to global food safety, public health, and agricultural sustainability. Traditional methods for mitigating aflatoxins, such as chemical and physical detoxification techniques, often raise concerns about environmental harm, nutrient loss, and potential toxicity. In contrast, green-synthesized nanomaterials have emerged as an environmentally friendly and effective solution for controlling aflatoxins. This study explores the potential of green-synthesized nanomaterials for aflatoxin mitigation, focusing on their mechanisms of action, effectiveness, and long-term applicability in agricultural and food safety contexts. A comprehensive review of 116 articles on the latest developments in green nanotechnology was used, focusing on the creation, characterization, and application of nanoparticles, including silver, zinc oxide, titanium dioxide, and iron-based nanomaterials. Green nanoparticles reduce aflatoxin load primarily through their antioxidant properties, which neutralize oxidative stress, and their high adsorption capacity, which binds aflatoxins and reduces their bioavailability. Photocatalytic degradation, adsorption, and enzymatic detoxification were also evaluated. The results indicate that green-synthesized nanoparticles exhibit high efficacy, biocompatibility, and minimal environmental impact, especially when compared to traditional detoxification methods. However, challenges such as nanoparticle stability, large-scale production, regulatory issues, and potential long-term toxicity still require further investigation. To advance this field, future studies should focus on refining green synthesis processes, enhancing nanoparticle stability, and exploring the integration of nanotechnology with biosensors and smart packaging for real-time aflatoxin monitoring. By advancing these sustainable technologies, this research aims to contribute to the development of effective and safe methods for aflatoxin mitigation, thereby supporting global food security, public health, and environmental sustainability.