Efficacy of Erbium and CO2 Genital Laser Treatment on Genitourinary Syndrome in Female Patients After Breast Cancer: A Scoping Review.

IF 2.2 3区 医学 Q2 DERMATOLOGY
Keila S T Ferreira, Nathalia S Guimarães, Gisele V de Oliveira
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引用次数: 0

Abstract

Objectives: This scoping review aimed to synthesize the existing scientific literature on the methods, tools, and strategies employed in vaginal laser therapy for treating genitourinary syndrome in breast cancer survivors.

Methods: A systematic search was conducted in August 2024 across six electronic databases-MEDLINE (via PubMed), Embase (Elsevier), Scopus (Elsevier), Cochrane Library (Central), Virtual Health Library (VHL), and Web of Science (Clarivate Analytics)-for studies reporting the use of CO2 or erbium lasers in breast cancer survivors. The search included articles in all languages and used MeSH terms and database-specific adaptations.

Results: A total of 2372 studies were identified through the electronic databases. After excluding 458 duplicates, 2134 titles and abstracts were screened. Thirty full-text records were assessed for eligibility, of which 10 were excluded for incomplete results and different technologies. Ultimately, 1189 patients out of 20 studies were selected for inclusion in this review: 14 studies used CO2 laser, 5 used erbium laser, and 1 used both technologies. This review showed that use of vaginal lasers to approach GSM in BSC patients is being used since 2017, and 13 out of 20 studies concluded for the safety and efficacy of vaginal laser to treat GSM in BCS patients, comparable to standard treatment.

Conclusion: Both CO2 and erbium lasers appear to be safe and effective treatment options for breast cancer survivors with genitourinary syndrome. New larger, multicenter studies are needed to enhance safety, standardize treatment protocols, and provide further evidence on the efficacy of these therapies in this patient population.

铒CO2生殖器激光治疗女性乳腺癌后泌尿生殖系统综合征的疗效综述
目的:本综述旨在综合现有的关于阴道激光治疗乳腺癌幸存者泌尿生殖系统综合征的方法、工具和策略的科学文献。方法:2024年8月,对medline(通过PubMed)、Embase(爱思唯尔)、Scopus(爱思唯尔)、Cochrane图书馆(Central)、虚拟健康图书馆(VHL)和Web of Science (Clarivate Analytics)这六个电子数据库进行了系统搜索,以报告在乳腺癌幸存者中使用CO2或铒激光的研究。搜索包括所有语言的文章,并使用MeSH术语和数据库特定的改编。结果:通过电子数据库共识别出2372项研究。在排除458个重复后,筛选了2134个标题和摘要。评估了30份全文记录的合格性,其中10份因结果不完整和技术不同而被排除在外。最终,20项研究中的1189名患者被纳入本综述:14项研究使用CO2激光,5项使用铒激光,1项使用两种技术。该综述显示,自2017年以来,在BCS患者中使用阴道激光治疗GSM, 20项研究中有13项得出结论,阴道激光治疗BCS患者GSM的安全性和有效性与标准治疗相当。结论:对于伴有泌尿生殖系统综合征的乳腺癌幸存者来说,CO2和铒激光似乎都是安全有效的治疗选择。需要新的更大规模的多中心研究来提高安全性,规范治疗方案,并为这些治疗在该患者群体中的有效性提供进一步的证据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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