The high-priority ethical issues of advanced paternal age: perspectives from a panel of experts in the fields of men reproduction and family building.

IF 3 1区 哲学 Q1 ETHICS
Vincent Couture, Émy Coiteux, Marianne Beaulieu, Timothey Bédard, Kévin Lavoie
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引用次数: 0

Abstract

Background: Research shows that the age of fathers at the time of conception is correlated with detrimental effect for the health of the future offspring. This situation raises ethical questions regarding the priority of the principle of reproductive autonomy of men of advanced age over the well-being of their future offspring. This problem leads to other normative implications such as the value of introducing limits to the use of medically assisted reproduction, and the development of public health interventions. For the moment, this ethical reflection is mostly speculative and calls to open up the discussion. The aim of this research was to survey experts, working in related fields to the topic of advanced paternal age (APA), regarding the top priority ethical issues of this emerging subject.

Methods: We recruited experts concerned by APA with backgrounds in health sciences, ethics, social work and reproductive medicine. We conducted a modified e-Delphi panel that lasted three rounds to build a consensual list of issues. The last round took the form of structured interviews exploring the results of the previous rounds.

Results: The top four issues according to the panel are: (1) Should APA be included as a criterion for prenatal genetic screening? (2) Should we raise awareness on reproductive health in relation to the age of fathers? (3) How can health-care providers support patients in the context of APA? (4) How can research inform the public without stigmatizing fathers of advanced age?

Conclusions: These exploratory results suggest that the issues of how to inform various audiences properly on APA are important concerns for experts.

Clinical trial number: Not applicable.

父亲高龄的高度优先伦理问题:男子生殖和家庭建设领域专家小组的观点。
背景:研究表明,父亲在受孕时的年龄对未来后代的健康有不利影响。这种情况提出了关于老年男子生殖自主原则优先于其未来后代福祉的伦理问题。这一问题导致其他规范方面的影响,例如限制使用医疗辅助生殖的价值,以及制定公共卫生干预措施。目前,这种伦理反思主要是推测性的,需要展开讨论。本研究的目的是调查在高龄父亲(APA)主题相关领域工作的专家,关于这一新兴主题的首要伦理问题。方法:招募健康科学、伦理学、社会工作和生殖医学背景的APA相关专家。我们进行了一个经过修改的e-Delphi小组,历时三轮,以建立一个共识的问题清单。最后一轮采用结构化访谈的形式,探讨前几轮的结果。结果:专家组认为最重要的四个问题是:(1)是否应将APA纳入产前遗传筛查的标准?(2)我们是否应该提高对与父亲年龄有关的生殖健康的认识?(3)在APA背景下,卫生保健提供者如何支持患者?(4)研究如何在不侮辱老年父亲的情况下告知公众?结论:这些探索性结果表明,如何正确地向不同的受众告知APA是专家关注的重要问题。临床试验号:不适用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Medical Ethics
BMC Medical Ethics MEDICAL ETHICS-
CiteScore
5.20
自引率
7.40%
发文量
108
审稿时长
>12 weeks
期刊介绍: BMC Medical Ethics is an open access journal publishing original peer-reviewed research articles in relation to the ethical aspects of biomedical research and clinical practice, including professional choices and conduct, medical technologies, healthcare systems and health policies.
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