Population norms of health-related quality of life in Iran: findings from a national EQ-5D-5L study.

IF 3.2 2区 医学 Q1 HEALTH CARE SCIENCES & SERVICES
Satar Rezaei
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Abstract

Background: Evaluating health-related quality of life (HRQoL) in the general population is essential for establishing benchmarks for health outcome assessments. This study aimed to generate population norms for the EQ-5D-5L dimensions, EQ-VAS (EuroQol-Visual Analogue Scale) scores, and EQ-5D-5L index scores in Iran, stratified by sex and age.

Methods: Data for this cross-sectional study were gathered through face-to-face interviews with 3,518 adults from the general population across nine provinces in Iran, employing a multistage sampling approach. Respondents assessed their own health state across the EQ-5D-5L dimensions-mobility, self-care, usual activities, pain/discomfort, and anxiety/depression-along with the EQ-VAS to evaluate their overall health. The EQ-5D-5L score was calculated using the value set derived from the Iranian general population. Dimension scores and index values (EQ-5D-5L index and EQ-VAS score) were analyzed using multiple logistic regression and generalized linear model (GLM), respectively.

Results: The estimated mean ± standard deviation [SD] of EQ-5D-5L index for the general population of Iran was 0.789 ± 0.258, while the EQ-VAS score was estimated at 74.34 ± 18.67. Among the study participants, 35.8% reported being in the best health state (11111), while the remaining 64.2% experienced problems in at least one of the five dimensions. The most commonly reported problems were related to anxiety/depression (49.2%), followed by pain/discomfort (45.3%). Regression analyses revealed that females reported significantly more problems across the five dimensions of the EQ-5D-5L and had lower EQ-5D-5L index and EQ-VAS scores compared to males. Anxiety/depression were more prevalent among younger individuals, while problems in other dimensions tended to increase with age.

Conclusions: The findings indicate that nearly two-thirds of respondents experienced problems in at least one dimension, with anxiety/depression being the most prevalent, particularly among younger individuals. Females reported lower utility scores and more problems across all dimensions in all age groups. To effectively improve the health status of the Iranian population and ensure optimal resource allocation, it is vital to develop and implement targeted interventions that specifically address the needs highlighted in this study.

伊朗与健康有关的生活质量人口标准:一项国家EQ-5D-5L研究的结果
背景:评估普通人群的健康相关生活质量(HRQoL)对于建立健康结果评估基准至关重要。本研究旨在生成伊朗EQ-5D-5L维度、EQ-VAS (EuroQol-Visual Analogue Scale)评分和EQ-5D-5L指数评分的人口规范,并按性别和年龄分层。方法:采用多阶段抽样方法,对伊朗9个省的3518名成年人进行面对面访谈,收集本横断面研究的数据。受访者通过EQ-5D-5L维度评估自己的健康状况——流动性、自我护理、日常活动、疼痛/不适和焦虑/抑郁——以及EQ-VAS来评估他们的整体健康状况。EQ-5D-5L评分使用来自伊朗一般人群的值集计算。各维度得分和指标值(EQ-5D-5L指数和EQ-VAS评分)分别采用多元logistic回归和广义线性模型(GLM)进行分析。结果:伊朗普通人群EQ-5D-5L指数估计均数±标准差[SD]为0.789±0.258,EQ-VAS评分估计为74.34±18.67。在研究参与者中,35.8%的人报告自己处于最佳健康状态(11111),而其余64.2%的人在五个维度中至少有一个方面存在问题。最常见的问题是焦虑/抑郁(49.2%),其次是疼痛/不适(45.3%)。回归分析显示,与男性相比,女性在EQ-5D-5L的五个维度上报告的问题明显更多,并且EQ-5D-5L指数和EQ-VAS评分较低。焦虑/抑郁在年轻人中更为普遍,而其他方面的问题往往随着年龄的增长而增加。结论:研究结果表明,近三分之二的受访者至少在一个方面遇到过问题,其中焦虑/抑郁最为普遍,尤其是在年轻人中。在所有年龄组中,女性报告的效用得分较低,在所有维度上都存在更多问题。为了有效改善伊朗人口的健康状况并确保资源的最佳分配,必须制定和实施有针对性的干预措施,具体解决本研究中强调的需求。
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来源期刊
CiteScore
7.30
自引率
2.80%
发文量
154
审稿时长
3-8 weeks
期刊介绍: Health and Quality of Life Outcomes is an open access, peer-reviewed, journal offering high quality articles, rapid publication and wide diffusion in the public domain. Health and Quality of Life Outcomes considers original manuscripts on the Health-Related Quality of Life (HRQOL) assessment for evaluation of medical and psychosocial interventions. It also considers approaches and studies on psychometric properties of HRQOL and patient reported outcome measures, including cultural validation of instruments if they provide information about the impact of interventions. The journal publishes study protocols and reviews summarising the present state of knowledge concerning a particular aspect of HRQOL and patient reported outcome measures. Reviews should generally follow systematic review methodology. Comments on articles and letters to the editor are welcome.
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