Magnetic Solid-Phase Extraction Based on C18 Nanoparticles for the Determination of Pesticides in Aquaculture Water Samples.

IF 4.2 2区化学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Molecules Pub Date : 2025-05-07 DOI:10.3390/molecules30092076

Margarita Kapsi, Vasileios Sakkas, Vasiliki Boti, Triantafyllos Albanis

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引用次数: 0

Abstract

In this study, C18-functionalized magnetic silica nanoparticles (Fe₃O₄@SiO₂@C18) were used as adsorbents for the magnetic solid-phase extraction (MSPE) of organic contaminants commonly applied to aquaculture water (organic booster biocides, herbicides, and insecticides) followed by Gas Chromatography coupled to Mass Spectrometry (GC-MS). The extraction conditions and efficiency of the nanoparticles for the determination of ten pesticides (atrazine, ethoxyquine, chlorothalonil, chlorpyriphos methyl, methyl parathion, chlorpyriphos, resmethrin, λ-cyhalothrin, permethrin, and irgarol) were thoroughly investigated. Several experimental parameters affecting the extraction efficiency such as the amount of sorbent, extraction time, and elution time were optimized by employing experimental designs as response surface methodology. Validation experiments showed that the average recoveries of target analytes were in the range of 60% to 99%. The optimized method exhibited good linearity (R² > 0.9901) and satisfactory precision (Relative Standard deviations, RSDs < 15%). The method detection limits ranged between 1.9 ng L^-1 and 62 ng L^-1. Finally, the MSPE method was successfully applied to aquaculture water samples collected from the Thesprotia region (N.W. Greece), Thermaikos Gulf (N. Greece) and Butrint (S.W. Albania).

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基于C18纳米颗粒的磁性固相萃取法测定水产养殖水样中农药

本研究以c18功能化的磁性二氧化硅纳米颗粒（Fe3O4@SiO2@C18）为吸附剂，采用气相色谱-质谱联用技术对水产养殖水体中常见的有机污染物（有机增强型杀菌剂、除草剂和杀虫剂）进行磁固相萃取（MSPE）。考察了纳米颗粒对阿特拉津、乙氧奎因、百菌清、甲基毒死蜱、甲基对硫磷、毒死蜱、异氰菊酯、λ-高效氯氰菊酯、氯菊酯、异氰菊酯等10种农药的萃取条件和萃取效率。采用实验设计作为响应面法，对吸附剂用量、提取时间、洗脱时间等影响提取效率的实验参数进行了优化。验证实验表明，目标分析物的平均回收率在60% ~ 99%范围内。优化后的方法线性良好（R2 < 0.9901），精密度满意（相对标准偏差，rsd < 15%）。方法检出限为1.9 ~ 62 ng L-1。最后，将MSPE方法成功应用于希腊西北部的Thesprotia地区、希腊北部的Thermaikos海湾和阿尔巴尼亚西南部的Butrint地区的水产养殖水样。

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来源期刊

Molecules 化学-有机化学

CiteScore

7.40

自引率

8.70%

发文量

7524

审稿时长

1.4 months

期刊介绍： Molecules (ISSN 1420-3049, CODEN: MOLEFW) is an open access journal of synthetic organic chemistry and natural product chemistry. All articles are peer-reviewed and published continously upon acceptance. Molecules is published by MDPI, Basel, Switzerland. Our aim is to encourage chemists to publish as much as possible their experimental detail, particularly synthetic procedures and characterization information. There is no restriction on the length of the experimental section. In addition, availability of compound samples is published and considered as important information. Authors are encouraged to register or deposit their chemical samples through the non-profit international organization Molecular Diversity Preservation International (MDPI). Molecules has been launched in 1996 to preserve and exploit molecular diversity of both, chemical information and chemical substances.