The stress-immune system axis: Exploring the interplay between stress and immunity.

4区 医学 Q3 Neuroscience
Progress in brain research Pub Date : 2025-01-01 Epub Date: 2025-03-10 DOI:10.1016/bs.pbr.2025.01.003
Muhammad Liaquat Raza
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引用次数: 0

Abstract

The chapter talks about how our body and mind respond to stress and how it affects our immune system. Stress reactions, especially the fight-or-flight reaction, are helpful at first but can be harmful if they last too long. Long-term stress, caused by hormones like cortisol and adrenaline, weakens the immune system and makes people more likely to get sick. Important brain chemicals like serotonin and norepinephrine help control how our immune system works. Also, the connection between our gut and brain is an important way that mental health affects how our immune system functions. Getting older and experiencing stress early in life can affect how our immune system works. Inflammation caused by stress is connected to health issues like heart disease, depression, and autoimmune diseases. There are ways to manage stress, like being mindful and having support from friends, are important for keeping your immune system healthy and lessening harm caused by stress.

压力-免疫系统轴:探索压力和免疫之间的相互作用。
这一章讨论了我们的身心如何应对压力,以及压力如何影响我们的免疫系统。压力反应,尤其是“战或逃”反应,一开始是有帮助的,但如果持续太久就会有害。由皮质醇和肾上腺素等激素引起的长期压力会削弱免疫系统,使人们更容易生病。重要的大脑化学物质,如血清素和去甲肾上腺素,帮助控制我们的免疫系统如何工作。此外,我们的肠道和大脑之间的联系是心理健康影响免疫系统功能的重要方式。年龄的增长和早年的压力会影响我们的免疫系统的工作方式。压力引起的炎症与心脏病、抑郁症和自身免疫性疾病等健康问题有关。管理压力的方法有很多,比如保持专注和得到朋友的支持,这对保持免疫系统健康和减少压力造成的伤害很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Progress in brain research
Progress in brain research 医学-神经科学
CiteScore
5.20
自引率
0.00%
发文量
174
审稿时长
6-12 weeks
期刊介绍: Progress in Brain Research is the most acclaimed and accomplished series in neuroscience. The serial is well-established as an extensive documentation of contemporary advances in the field. The volumes contain authoritative reviews and original articles by invited specialists. The rigorous editing of the volumes assures that they will appeal to all laboratory and clinical brain research workers in the various disciplines: neuroanatomy, neurophysiology, neuropharmacology, neuroendocrinology, neuropathology, basic neurology, biological psychiatry and the behavioral sciences.
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