Risk Factors of Retinopathy of Prematurity: A Prospective Study.

IF 0.9 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Indian journal of public health Pub Date : 2025-01-01 Epub Date: 2025-03-21 DOI:10.4103/ijph.ijph_1514_23

Bindu K Sankar, Hrishikesh Amin, P Pappa, K M Riaz

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引用次数: 0

Abstract

Abstract: A prospective observational study was conducted to find out the risk factors of retinopathy of prematurity (ROP). A total of 311 preterm infants with gestational age ≤34 weeks and birth weight ≤2000 g admitted to neonatal intensive care unit (NICU) were screened by Indirect ophthalmoscopy. Both univariate (Chi-square test) and multivariate regression analysis were used for analyzing risk factors. Any stage of ROP was seen in 58 (18.64%) infants, Plus disease in 13 eyes of 7 infants, and aggressive posterior retinopathy of prematurity in 1 infant. In univariate analysis, gestational diabetes, type of delivery, gestational age, birth weight, hemoglobin at birth, Apgar at 1 and 5 min, duration of oxygen administration, ventilator support, continuous positive airway pressure, hood, nasal prongs, hyaline membrane disease, surfactant, PDA, sepsis, and weight on postnatal day 15 showed statistically significant association with ROP. Gestational diabetes (P = 0.029), duration of oxygen administration (P = 0.003), and gestational age (P = 0.012) were statistically significant in multivariate analysis.

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早产儿视网膜病变危险因素：一项前瞻性研究。

摘要：本研究旨在探讨早产儿视网膜病变（retinopathy of prematurity， ROP）的危险因素。对新生儿重症监护病房（NICU）收治的胎龄≤34周、出生体重≤2000 g的早产儿311例进行间接眼镜检查。危险因素分析采用单因素（卡方检验）和多因素回归分析。58例（18.64%）患儿出现任何阶段的ROP， 7例患儿13只眼出现病变，1例患儿出现侵袭性早产儿后视网膜病变。在单因素分析中，妊娠糖尿病、分娩类型、胎龄、出生体重、出生时血红蛋白、1和5分钟时Apgar、给氧时间、呼吸机支持、持续气道正压、头罩、鼻尖、透明膜病、表面活性剂、PDA、败血症和出生后第15天体重与ROP有统计学意义的关联。妊娠期糖尿病（P = 0.029）、给氧时间（P = 0.003）、胎龄（P = 0.012）在多因素分析中均有统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian journal of public health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

2.40

自引率

0.00%

发文量

审稿时长

21 weeks

期刊介绍： Indian Journal of Public Health is a peer-reviewed international journal published Quarterly by the Indian Public Health Association. It is indexed / abstracted by the major international indexing systems like Index Medicus/MEDLINE, SCOPUS, PUBMED, etc. The journal allows free access (Open Access) to its contents and permits authors to self-archive final accepted version of the articles. The Indian Journal of Public Health publishes articles of authors from India and abroad with special emphasis on original research findings that are relevant for developing country perspectives including India. The journal considers publication of articles as original article, review article, special article, brief research article, CME / Education forum, commentary, letters to editor, case series reports, etc. The journal covers population based studies, impact assessment, monitoring and evaluation, systematic review, meta-analysis, clinic-social studies etc., related to any domain and discipline of public health, specially relevant to national priorities, including ethical and social issues. Articles aligned with national health issues and policy implications are prefered.