A Customized Medication Adherence Enhancement Program for Adolescents and Young Adults With ADHD (CAE-ADHD): Primary Outcomes.

IF 2.7 3区 医学 Q2 PSYCHIATRY
Journal of Attention Disorders Pub Date : 2025-06-01 Epub Date: 2025-04-18 DOI:10.1177/10870547251328526
Molly McVoy, Salayna M Abdallah, Emma Church, Joy Yala, Farren Briggs, Jennifer B Levin
{"title":"A Customized Medication Adherence Enhancement Program for Adolescents and Young Adults With ADHD (CAE-ADHD): Primary Outcomes.","authors":"Molly McVoy, Salayna M Abdallah, Emma Church, Joy Yala, Farren Briggs, Jennifer B Levin","doi":"10.1177/10870547251328526","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>ADHD is a generally persistent neurodevelopmental condition that can have significant consequences if left untreated, and medication, often in conjunction with psychotherapy, is the first-line treatment with well-established efficacy. Adolescents and young adults (AYAs) represent a particularly vulnerable and understudied subgroup and there remains a significant concern regarding transition to treatment independence, treatment engagement and medication adherence in this population. We report the results from a pilot trial evaluating Customized Adherence Enhancement-ADHD (CAE-ADHD), a psychosocial intervention for AYAs with ADHD, aimed to increase independence in managing ADHD and improve ADHD symptoms.</p><p><strong>Methods: </strong>We used an iterative process to modify an existing psychosocial intervention to address engagement, independence, and adherence in AYAs with ADHD, originally developed for AYAs with bipolar disorder. To develop the CAE-ADHD intervention, we conducted focus groups and cognitive interviews with AYA with ADHD. We then conducted a pilot feasibility and efficacy study in AYAs with ADHD (<i>n</i> = 12) with follow-up visits at 8 and 12 weeks into the study.</p><p><strong>Results: </strong>The sample consisted of 12 participants ages 16 to 24 years with a diagnosis of ADHD, obtained via self-report, and currently prescribed stimulant medication. Mean age of the sample was 19.5 years, 58.33% female, 25% non-White. Participation and retention were strong with 93.33% of sessions completed overall and 10/12 participants completing all sessions. AYAs showed a trend toward improvement in ADHD symptoms as measured by the ADHD RS-5, statistically significant improvement in transition readiness and ADHD knowledge. There was no significant change in adherence.</p><p><strong>Conclusions: </strong>This first of its kind feasibility and efficacy pilot study for a novel intervention, CAE-ADHD, found high engagement and improvement in ADHD symptoms, transition readiness, and ADHD knowledge from baseline to week 12.</p>","PeriodicalId":15237,"journal":{"name":"Journal of Attention Disorders","volume":"29 8","pages":"591-601"},"PeriodicalIF":2.7000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Attention Disorders","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10870547251328526","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/4/18 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: ADHD is a generally persistent neurodevelopmental condition that can have significant consequences if left untreated, and medication, often in conjunction with psychotherapy, is the first-line treatment with well-established efficacy. Adolescents and young adults (AYAs) represent a particularly vulnerable and understudied subgroup and there remains a significant concern regarding transition to treatment independence, treatment engagement and medication adherence in this population. We report the results from a pilot trial evaluating Customized Adherence Enhancement-ADHD (CAE-ADHD), a psychosocial intervention for AYAs with ADHD, aimed to increase independence in managing ADHD and improve ADHD symptoms.

Methods: We used an iterative process to modify an existing psychosocial intervention to address engagement, independence, and adherence in AYAs with ADHD, originally developed for AYAs with bipolar disorder. To develop the CAE-ADHD intervention, we conducted focus groups and cognitive interviews with AYA with ADHD. We then conducted a pilot feasibility and efficacy study in AYAs with ADHD (n = 12) with follow-up visits at 8 and 12 weeks into the study.

Results: The sample consisted of 12 participants ages 16 to 24 years with a diagnosis of ADHD, obtained via self-report, and currently prescribed stimulant medication. Mean age of the sample was 19.5 years, 58.33% female, 25% non-White. Participation and retention were strong with 93.33% of sessions completed overall and 10/12 participants completing all sessions. AYAs showed a trend toward improvement in ADHD symptoms as measured by the ADHD RS-5, statistically significant improvement in transition readiness and ADHD knowledge. There was no significant change in adherence.

Conclusions: This first of its kind feasibility and efficacy pilot study for a novel intervention, CAE-ADHD, found high engagement and improvement in ADHD symptoms, transition readiness, and ADHD knowledge from baseline to week 12.

针对患有ADHD的青少年和年轻成人(CAE-ADHD)定制的药物依从性增强方案:主要结果。
背景:多动症是一种普遍存在的神经发育疾病,如果不及时治疗,可能会产生严重后果,药物治疗,通常与心理治疗相结合,是一线治疗方法,疗效良好。青少年和年轻人(AYAs)是一个特别脆弱和研究不足的亚组,在这一人群中,向治疗独立、治疗参与和药物依从性的过渡仍然值得关注。我们报告了一项评估自定义依从性增强-ADHD (CAE-ADHD)的试点试验的结果,这是一种针对患有ADHD的aya的社会心理干预,旨在提高管理ADHD的独立性并改善ADHD症状。方法:我们使用了一个迭代过程来修改现有的社会心理干预措施,以解决患有多动症的青少年的参与、独立性和依从性,最初是为患有双相情感障碍的青少年开发的。为了开发CAE-ADHD干预措施,我们对患有ADHD的AYA进行了焦点小组和认知访谈。然后,我们对患有多动症的青少年(n = 12)进行了可行性和有效性的试点研究,并在研究开始后的8周和12周进行了随访。结果:样本包括12名年龄在16至24岁之间的参与者,他们通过自我报告被诊断为多动症,目前正在服用兴奋剂药物。样本平均年龄19.5岁,女性58.33%,非白人25%。参与者和保留率很高,93.33%的课程完成了全部课程,10/12的参与者完成了所有课程。通过ADHD RS-5测量,aya显示ADHD症状有改善的趋势,在过渡准备和ADHD知识方面有统计学上显著的改善。依从性没有显著变化。结论:这是首个针对CAE-ADHD这一新型干预措施的可行性和有效性的试点研究,发现从基线到第12周,ADHD症状、过渡准备和ADHD知识的高度参与和改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
7.60
自引率
6.70%
发文量
71
审稿时长
6-12 weeks
期刊介绍: Journal of Attention Disorders (JAD) focuses on basic and applied science concerning attention and related functions in children, adolescents, and adults. JAD publishes articles on diagnosis, comorbidity, neuropsychological functioning, psychopharmacology, and psychosocial issues. The journal also addresses practice, policy, and theory, as well as review articles, commentaries, in-depth analyses, empirical research articles, and case presentations or program evaluations.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信