Clinical Recommendations for the Perioperative Management of Biologic Medications for Nonrheumatologic Diseases in Total Joint Arthroplasty.

IF 1.7 Q2 SURGERY

JBJS Reviews Pub Date : 2025-04-28 eCollection Date: 2025-04-01 DOI:10.2106/JBJS.RVW.25.00004

Andrew R Moya, Pooya Tehrany, Kassem Ghayyad, Ramakanth Yakkanti, Andrew Pepper

引用次数: 0

Abstract

» Managing biologic therapies in nonrheumatologic patients undergoing total joint arthroplasty (TJA) poses unique risks, such as infection, and wound healing issues, yet guidelines are limited.» Some agents may be continued during the perioperative period, while others may need to be temporarily withheld before surgery.» The absence of clear perioperative guidelines for patients on biologics underscores the need for evidence-based protocols to support optimal surgical outcomes.» A deeper understanding of biologic pharmacodynamics in the perioperative period can help manage risks, particularly as the demand for TJAs in biologic-treated patients grows.

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全关节置换术中非风湿病生物药物围手术期管理的临床建议

»对接受全关节置换术（TJA）的非风湿病患者进行生物治疗存在独特的风险，如感染和伤口愈合问题，但指南有限。一些药物可以在围手术期继续使用，而另一些可能需要在手术前暂时停用。缺乏明确的生物制剂患者围手术期指南，强调需要循证方案来支持最佳手术结果。»对围手术期生物药效学的深入了解可以帮助管理风险，特别是随着生物治疗患者对TJAs需求的增长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

JBJS Reviews SURGERY-

CiteScore

4.40

自引率

4.30%

发文量

132

期刊介绍： JBJS Reviews is an innovative review journal from the publishers of The Journal of Bone & Joint Surgery. This continuously published online journal provides comprehensive, objective, and authoritative review articles written by recognized experts in the field. Edited by Thomas A. Einhorn, MD, and a distinguished Editorial Board, each issue of JBJS Reviews, updates the orthopaedic community on important topics in a concise, time-saving manner, providing expert insights into orthopaedic research and clinical experience. Comprehensive reviews, special features, and integrated CME provide orthopaedic surgeons with valuable perspectives on surgical practice and the latest advances in the field within twelve subspecialty areas: Basic Science, Education & Training, Elbow, Ethics, Foot & Ankle, Hand & Wrist, Hip, Infection, Knee, Oncology, Pediatrics, Pain Management, Rehabilitation, Shoulder, Spine, Sports Medicine, Trauma.