Peng Zhang, Fan Lin, Fei Ma, Yuting Chen, Yuhang Liu, Xiaoli Feng, Siyi Fang, Haowei Zhang, Shuna Xiao, Xiangli Yang, Dun Li, Dao Wen Wang, Xiaoyun Yang, Qiang Li
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引用次数: 0
Abstract
Background: Given the biases and ethical concerns of AI models, the fully automatic diagnosis of diseases in clinical settings is challenging. In contrast, clinician-AI collaboration is considered essential to ensure the validity and reliability of utilizing AI models in clinical practice. However, effective strategies for clinician-AI collaboration remain largely unexplored.
Methods: This study proposed a three-step general clinician-AI collaboration pipeline aimed at improving disease diagnosis efficiency: first, utilizing large real-world clinical datasets to evaluate and clarify clinicians' diagnostic strengths/weaknesses; second, developing an AI model to complement clinicians' weakness in disease diagnosis; and finally, proposing a clinician-AI collaboration strategy to leverage the strengths of both AI and clinicians. The effectiveness of this pipeline was validated through a study focusing on clinical paroxysmal atrial fibrillation (PAF) detection, utilizing 24-h Holter recordings from over 30,000 patients.
Findings: In PAF detection, clinicians alone required a significant amount of time to identify the data and still overlooked 13.7% of PAF patients but successfully identified all non-atrial fibrillation (AF) patients. Conversely, AI alone rarely missed PAF patients but misidentified 23.3% of non-AF patients as having PAF. After implementing the proposed clinician-AI collaboration strategy, all patients were correctly identified, and clinicians' workload was reduced by 76.7%.
Conclusions: This study improves both the efficiency and reliability of PAF detection, bridging the gap between AI model development and its clinical application, thereby effectively promoting the application of AI models in clinical AF screening.
Funding: This study was supported in part by the National Natural Science Foundation of China.
期刊介绍：
Med is a flagship medical journal published monthly by Cell Press, the global publisher of trusted and authoritative science journals including Cell, Cancer Cell, and Cell Reports Medicine. Our mission is to advance clinical research and practice by providing a communication forum for the publication of clinical trial results, innovative observations from longitudinal cohorts, and pioneering discoveries about disease mechanisms. The journal also encourages thought-leadership discussions among biomedical researchers, physicians, and other health scientists and stakeholders. Our goal is to improve health worldwide sustainably and ethically.
Med publishes rigorously vetted original research and cutting-edge review and perspective articles on critical health issues globally and regionally. Our research section covers clinical case reports, first-in-human studies, large-scale clinical trials, population-based studies, as well as translational research work with the potential to change the course of medical research and improve clinical practice.
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