{"title":"A rare case of lethal lactic acid poisoning: an autopsy case report.","authors":"Deepu Mathew, Keerthi Kumaran, Alagarasan Naveen, Ambika Prasad Patra, Pampa Ch Toi","doi":"10.1007/s12024-025-01005-8","DOIUrl":null,"url":null,"abstract":"<p><p>More than 700,000 people die due to suicide every year, and ingestion of pesticides, hanging, and firearms are among the most commonly used suicide methods globally. Although corrosives are among the least preferred agents for suicide due to the extreme pain caused and the possibility of prolonged suffering instead of immediate death, cases of ingestion continue to be observed. Commonly ingested corrosive substances include acids such as hydrochloric and sulfuric acid, alkalis such as sodium and potassium hydroxide, heavy metal salts, formalin, and iodine tincture. However, previous literature has not reported cases of poisoning with lactic acid preparations in adults. In this report, we discuss the death of a 67-year-old male following the consumption of Lactisan, a commercial preparation of lactic acid used in the dairy industry. The diagnosis and management of lactic acid poisoning pose challenges due to the lack of any previous data and the short half-life of lactic acid in the bloodstream. The laboratory investigation showed severe lactic acidosis. We discuss in detail the gross and microscopic features of lactic acid poisoning. This case report emphasizes the need for awareness among healthcare professionals about such uncommon but potentially fatal poisonings.</p>","PeriodicalId":12449,"journal":{"name":"Forensic Science, Medicine and Pathology","volume":" ","pages":""},"PeriodicalIF":1.5000,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Forensic Science, Medicine and Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s12024-025-01005-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, LEGAL","Score":null,"Total":0}
引用次数: 0
Abstract
More than 700,000 people die due to suicide every year, and ingestion of pesticides, hanging, and firearms are among the most commonly used suicide methods globally. Although corrosives are among the least preferred agents for suicide due to the extreme pain caused and the possibility of prolonged suffering instead of immediate death, cases of ingestion continue to be observed. Commonly ingested corrosive substances include acids such as hydrochloric and sulfuric acid, alkalis such as sodium and potassium hydroxide, heavy metal salts, formalin, and iodine tincture. However, previous literature has not reported cases of poisoning with lactic acid preparations in adults. In this report, we discuss the death of a 67-year-old male following the consumption of Lactisan, a commercial preparation of lactic acid used in the dairy industry. The diagnosis and management of lactic acid poisoning pose challenges due to the lack of any previous data and the short half-life of lactic acid in the bloodstream. The laboratory investigation showed severe lactic acidosis. We discuss in detail the gross and microscopic features of lactic acid poisoning. This case report emphasizes the need for awareness among healthcare professionals about such uncommon but potentially fatal poisonings.
期刊介绍:
Forensic Science, Medicine and Pathology encompasses all aspects of modern day forensics, equally applying to children or adults, either living or the deceased. This includes forensic science, medicine, nursing, and pathology, as well as toxicology, human identification, mass disasters/mass war graves, profiling, imaging, policing, wound assessment, sexual assault, anthropology, archeology, forensic search, entomology, botany, biology, veterinary pathology, and DNA. Forensic Science, Medicine, and Pathology presents a balance of forensic research and reviews from around the world to reflect modern advances through peer-reviewed papers, short communications, meeting proceedings and case reports.