Short-Wavelength and Infrared Autofluorescence Imaging in Pachychoroid Neovasculopathy.

Q2 Medicine

Vision (Switzerland) Pub Date : 2025-04-21 DOI:10.3390/vision9020038

Norihiko Nakagawa, Takuya Shunto, Issei Nishiyama, Kohei Maruyama, Miki Sawa

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Abstract

Purpose: The purpose of this paper is to investigate the relationship between short-wavelength autofluorescence (SWAF) and infrared autofluorescence (IRAF) patterns in pachychoroid neovasculopathy (PNV) with serous retinal detachment (SRD).

Methods: This study used an observational case series of 62 eyes of 58 consecutive patients diagnosed with symptomatic PNV from January 2019 and October 2021 at a single institution. SWAF and IRAF patterns were analyzed with disease chronicity, and autofluorescence changes in macular neovascularization (MNV) were assessed in two images.

Results: SWAF patterns and the mean duration of symptoms were as follows: blocked (15 eyes, 24%), 1.0 months; mottled (8 eyes, 13%), 2.8 months; hyper (24 eyes, 39%), 5.0 months; hyper/hypo (10 eyes, 16%), 7.0 months; descending tract (5 eyes, 8%), 12.0 months (p < 0.01). IRAF patterns and the mean duration of symptoms were as follows: blocked (17 eyes, 27%), 1.0 months; hyper (22 eyes, 35%), 4.0 months; mixed/hyper dominant (9 eyes, 15%), 5.0 months; mixed/hypo dominant (9 eyes, 15%), 6.8 months; descending tract (5 eyes, 8%), 12.0 months (p < 0.01). Abnormal autofluorescence corresponding to MNV lesion was seen in 34 eyes (55%) with SWAF and 59 eyes (95%) with IRAF (p < 0.01).

Conclusions: SWAF and IRAF show multiple patterns and are related to disease chronicity in symptomatic PNV. IRAF could be helpful in detecting the lesion of MNV.

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厚脉络膜血管病的短波长和红外自身荧光成像。

目的：探讨厚脉络膜新生血管病变（PNV）伴浆液性视网膜脱离（SRD）的短波长自身荧光（swf）和红外自身荧光（IRAF）模式的关系。方法：本研究使用了2019年1月至2021年10月在同一家机构连续诊断为症状性PNV的58例患者的62只眼睛的观察病例系列。分析SWAF和IRAF模式与疾病的慢性关系，并在两幅图像中评估黄斑新生血管（MNV）的自身荧光变化。结果：SWAF分型及平均症状持续时间如下：阻塞（15眼，24%），1.0个月；斑驳（8眼，13%），2.8个月；Hyper(24眼，39%)，5.0个月；Hyper / hypoo(10眼，16%)，7.0个月；降支（5眼，8%），12.0个月（p < 0.01）。IRAF分型及平均症状持续时间如下：阻塞（17眼，27%），1.0个月；Hyper(22眼，35%)，4.0个月；混合型/超显性型（9眼，15%），5.0个月；混合型/次显性型（9眼，15%），6.8个月；降支（5眼，8%），12.0个月（p < 0.01）。swf组和IRAF组分别有34眼（55%）和59眼（95%）出现与MNV病变相应的自身荧光异常（p < 0.01）。结论：症状性PNV患者swf和IRAF表现出多种模式，并与疾病的慢性性有关。IRAF有助于检测MNV的病变。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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