Standardized Gene Nomenclature for Chicken Scavenger Receptors.

Abstract

Scavenger Receptors (SCARs) are a heterogeneous group involved in innate immunity and immunomodulation. We provided standardized nomenclature for chicken SCAR genes in line with other vertebrate nomenclatures. Chicken SCAR genes orthologous to human genes are assigned the same gene names and symbols. Novel SCAR genes were assessed to determine their appropriate class and assigned nomenclature in line with this classification. Notably, chicken has expansions of the MRC and DMBT genes, and the number of these paralogs varies across Sauropsida species. In addition, we identified and classified a further 15 novel SCAR genes, predominantly SCAR class I genes.