Bibliometric and Visual Analysis of Alzheimer's Disease and Herpes Simplex Virus Type 1 Infection Between 1990 and 2024.

IF 2.7 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Journal of Multidisciplinary Healthcare Pub Date : 2025-04-15 eCollection Date: 2025-01-01 DOI:10.2147/JMDH.S514397
Hongling Ren, Ruiyao Song, Hairong Wang, Qingyan Zeng, Yu Fu, Yunchu Guo, Ying Xie, Yusong Ge
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引用次数: 0

Abstract

Background: Recently, some studies suggested that Herpes simplex virus type 1 (HSV-1) infection is an important environmental factor for Alzheimer's disease(AD). The literature on research about HSV-1 infection and AD is emerging. This study used the bibliometric method to investigate the relationship between HSV-1 infection and AD.

Methods: We searched the Web of Science Core Collection for relevant literature on AD and HSV-1 from 1990 to 2024. Bibliometric and visualization analyses were performed using VOSviewer and CiteSpace.

Results: From 1990 to 2024, the number of publications showed an increasing trend. The United States made the largest contributions in productivity. The University of Manchester was the most productive organization. Professor Ruth F. Itzhaki was the most influential researcher. The Journal of Alzheimer's Disease had published the most articles. Research on the mechanisms by which HSV infection contributes to AD remains a hotspot in the field, and future studies may further focus on antiviral therapeutic strategies targeting HSV-1 infection.

Conclusion: Our analysis provides basic information about research in AD and HSV-1. The current research hotspots in this field mainly include the mechanism of AD caused by HSV-1, and antiviral drugs to treat or prevent AD.

1990年至2024年间阿尔茨海默病和单纯疱疹病毒1型感染的文献计量学和视觉分析。
背景:近年来,一些研究表明,单纯疱疹病毒1型(HSV-1)感染是阿尔茨海默病(AD)的重要环境因素。关于1型单纯疱疹病毒感染与AD的研究文献越来越多。本研究采用文献计量学方法探讨1型单纯疱疹病毒感染与AD的关系。方法:检索Web of Science Core Collection 1990 - 2024年AD和HSV-1的相关文献。使用VOSviewer和CiteSpace进行文献计量学和可视化分析。结果:1990 - 2024年,论文发表数量呈上升趋势。美国在生产力方面的贡献最大。曼彻斯特大学是最有生产力的机构。Ruth F. Itzhaki教授是最有影响力的研究者。《阿尔茨海默病杂志》发表的文章最多。对HSV感染导致AD的机制的研究仍然是该领域的热点,未来的研究可能会进一步关注针对HSV-1感染的抗病毒治疗策略。结论:我们的分析为AD和HSV-1的研究提供了基本信息。目前该领域的研究热点主要包括HSV-1引起AD的机制,以及治疗或预防AD的抗病毒药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Multidisciplinary Healthcare
Journal of Multidisciplinary Healthcare Nursing-General Nursing
CiteScore
4.60
自引率
3.00%
发文量
287
审稿时长
16 weeks
期刊介绍: The Journal of Multidisciplinary Healthcare (JMDH) aims to represent and publish research in healthcare areas delivered by practitioners of different disciplines. This includes studies and reviews conducted by multidisciplinary teams as well as research which evaluates or reports the results or conduct of such teams or healthcare processes in general. The journal covers a very wide range of areas and we welcome submissions from practitioners at all levels and from all over the world. Good healthcare is not bounded by person, place or time and the journal aims to reflect this. The JMDH is published as an open-access journal to allow this wide range of practical, patient relevant research to be immediately available to practitioners who can access and use it immediately upon publication.
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