Bacterial exotoxins in medicine: potential value and perspectives.

IF 3.2 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL
International Journal of Medical Sciences Pub Date : 2025-03-31 eCollection Date: 2025-01-01 DOI:10.7150/ijms.110104
Yuming Xiao, Zhou Yan, Fangyuan Ren, Yurong Tan
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引用次数: 0

Abstract

Bacterial exotoxins are protein- or peptide-based substances secreted by bacteria with high toxicity and specificity. They have diverse mechanisms of action on host cells, leading to host injury by destroying the cellular structure or interfering with physiological functions. With the continuous progress in biotechnology, bacterial exotoxins have broad application prospects in immunotherapy, vaccine development, drug design, and other fields. Appropriate modification of exotoxins can lead to the preparation of highly efficient immune agents and targeted drugs, which brings new hope for overcoming difficult diseases. This study provides a comprehensive and in-depth introduction to the application of bacterial exotoxins in the field of medicine and further explores the potential value of bacterial exotoxins, which is expected to make greater contributions to human health in the future.

细菌外毒素在医学中的潜在价值和前景。
细菌外毒素是细菌分泌的蛋白质或肽类物质,具有高毒性和特异性。它们对宿主细胞有多种作用机制,通过破坏细胞结构或干扰生理功能而导致宿主损伤。随着生物技术的不断进步,细菌外毒素在免疫治疗、疫苗研制、药物设计等领域有着广阔的应用前景。对外毒素进行适当的修饰,可以制备出高效的免疫制剂和靶向药物,为攻克疑难疾病带来新的希望。本研究全面深入地介绍了细菌外毒素在医学领域的应用,进一步挖掘了细菌外毒素的潜在价值,有望在未来为人类健康做出更大的贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Journal of Medical Sciences
International Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-
CiteScore
7.20
自引率
0.00%
发文量
185
审稿时长
2.7 months
期刊介绍: Original research papers, reviews, and short research communications in any medical related area can be submitted to the Journal on the understanding that the work has not been published previously in whole or part and is not under consideration for publication elsewhere. Manuscripts in basic science and clinical medicine are both considered. There is no restriction on the length of research papers and reviews, although authors are encouraged to be concise. Short research communication is limited to be under 2500 words.
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