{"title":"Fluorescent and Colorimetric Methods for Mercury Sensing: Trends and Applications.","authors":"Duraisamy Udhayakumari","doi":"10.1007/s10895-025-04356-1","DOIUrl":null,"url":null,"abstract":"<p><p>Mercury contamination poses a profound threat to both environmental integrity and human well-being due to its extreme toxicity and strong bioaccumulative properties. Consequently, there is an increasing imperative for detection methodologies that exhibit exceptional sensitivity, selectivity, and efficiency in identifying mercury ions (Hg<sup>2</sup>⁺) with rapid response times. Among the diverse array of analytical techniques, fluorescent and colorimetric sensors have emerged as highly promising due to their operational simplicity, remarkable sensitivity, and capability for real-time monitoring. This review delves into recent advancements in these sensing modalities, with a particular emphasis on cutting-edge detection mechanisms, nanomaterial-enhanced strategies, and innovative probe architectures. Finally, this review critically examines the prevailing challenges and explores future perspectives for these technologies in pivotal domains such as environmental surveillance, food safety, and biomedical diagnostics.</p>","PeriodicalId":15800,"journal":{"name":"Journal of Fluorescence","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Fluorescence","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1007/s10895-025-04356-1","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
Mercury contamination poses a profound threat to both environmental integrity and human well-being due to its extreme toxicity and strong bioaccumulative properties. Consequently, there is an increasing imperative for detection methodologies that exhibit exceptional sensitivity, selectivity, and efficiency in identifying mercury ions (Hg2⁺) with rapid response times. Among the diverse array of analytical techniques, fluorescent and colorimetric sensors have emerged as highly promising due to their operational simplicity, remarkable sensitivity, and capability for real-time monitoring. This review delves into recent advancements in these sensing modalities, with a particular emphasis on cutting-edge detection mechanisms, nanomaterial-enhanced strategies, and innovative probe architectures. Finally, this review critically examines the prevailing challenges and explores future perspectives for these technologies in pivotal domains such as environmental surveillance, food safety, and biomedical diagnostics.
期刊介绍：
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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