Investigating the Effects of Reconstruction Conditions on Image Quality and Radiomic Analysis in Photon-counting Computed Tomography.

IF 0.7 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Journal of Medical Physics Pub Date : 2025-01-01 Epub Date: 2025-03-24 DOI:10.4103/jmp.jmp_114_24

Miyu Ohata, Ryohei Fukui, Yusuke Morimitsu, Daichi Kobayashi, Takatsugu Yamauchi, Noriaki Akagi, Mitsugi Honda, Aiko Hayashi, Koshi Hasegawa, Katsuhiro Kida, Sachiko Goto, Takao Hiraki

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引用次数: 0

Abstract

Introduction: Photon-counting computed tomography (CT) is equipped with an adaptive iterative reconstruction method called quantum iterative reconstruction (QIR), which allows the intensity to be changed during image reconstruction. It is known that the reconstruction conditions of CT images affect the analysis results when performing radiomic analysis. The aim of this study is to investigate the effect of QIR intensity on image quality and radiomic analysis of renal cell carcinoma (RCC).

Materials and methods: The QIR intensities were selected as off, 2 and 4. The image quality evaluation items considered were task-based transfer function (TTF), noise power spectrum (NPS), and low-contrast object specific contrast-to-noise ratio (CNR_LO). The influence on radiomic analysis was assessed using the discrimination accuracy of clear cell RCC.

Results: For image quality evaluation, TTF and NPS values were lower and CNR_LO values were higher with increasing QIR intensity; for radiomic analysis, sensitivity, specificity, and accuracy were higher with increasing QIR intensity. Principal component analysis and receiver operating characteristics analysis also showed higher values with increasing QIR intensity.

Conclusion: It was confirmed that the intensity of the QIR intensity affects both the image quality and the radiomic analysis.

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研究重建条件对光子计数计算机断层成像质量和放射学分析的影响。

简介：光子计数计算机断层扫描（CT）具有一种自适应迭代重建方法，称为量子迭代重建（QIR），它允许在图像重建过程中改变强度。众所周知，在进行放射组学分析时，CT图像的重建条件会影响分析结果。本研究的目的是探讨QIR强度对肾癌（RCC）图像质量和放射组学分析的影响。材料和方法：QIR强度分别为off、2和4。考虑的图像质量评估项目包括基于任务的传递函数（TTF）、噪声功率谱（NPS）和低对比度对象特定的噪比（CNRLO）。利用透明细胞RCC的鉴别准确度评估对放射组学分析的影响。结果：在图像质量评价中，随着QIR强度的增加，TTF和NPS值降低，CNRLO值升高；放射组学分析的灵敏度、特异性和准确性随着QIR强度的增加而提高。主成分分析和接收机工作特性分析也随QIR强度的增加而增加。结论：QIR强度对图像质量和放射学分析均有影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Physics RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

CiteScore

1.10

自引率

11.10%

发文量

审稿时长

30 weeks

期刊介绍： JOURNAL OF MEDICAL PHYSICS is the official journal of Association of Medical Physicists of India (AMPI). The association has been bringing out a quarterly publication since 1976. Till the end of 1993, it was known as Medical Physics Bulletin, which then became Journal of Medical Physics. The main objective of the Journal is to serve as a vehicle of communication to highlight all aspects of the practice of medical radiation physics. The areas covered include all aspects of the application of radiation physics to biological sciences, radiotherapy, radiodiagnosis, nuclear medicine, dosimetry and radiation protection. Papers / manuscripts dealing with the aspects of physics related to cancer therapy / radiobiology also fall within the scope of the journal.