Does Nutritional Therapy Reduce Disability and Improve Activities of Daily Living After a Stroke? - A Cochrane Review Summary with Commentary.

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

NeuroRehabilitation Pub Date : 2025-03-01 Epub Date: 2025-04-22 DOI:10.1177/10538135251327280

Francesca Cecchi

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引用次数: 0

Abstract

BackgroundMalnutrition can severely impact post-stroke functional recovery, but the effects of nutritional therapy (NT) on disability and activities of daily living (ADL) after stroke are not thoroughly investigated.Objectivesthe aim of the Cochrane Review by Sakai et al. (2023) was to evaluate the effectiveness of NT in reducing disability and improving ADL after stroke. The aim of this Corner is to provide a summary of Sakai et al. with comments from a rehabilitation perspective.Methodsrandomised controlled trials (RCTs) enrolling persons with stroke, investigating NT (defined as the administration of supplemental nutrients), compared with placebo, usual care (UC), or another type of NT were searched. Disability (modified Rankin score-mRS) and activities of daily living (ADL) were the primary outcomes.ResultsThe review included 52 trials (11,926 participants) with most studies conducted in the acute phase (36) and 25 types of supplements used. There was no difference in disability nor all-cause mortality, but oral energy and protein supplements may improve ADL. There was a higher risk of diarrohea, hyper- and hypoglycemia in participants receiving NT.ConclusionsThe effects of NT on disability and ADL after stroke is still uncertain, while NT may associate to increased adverse events. Future research should focus on targeted nutritional interventions to improve function after stroke, based on a theoretical rationale.

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营养疗法能减少中风后的残疾并改善日常生活活动吗？- Cochrane综述摘要及评论。

营养不良会严重影响脑卒中后的功能恢复，但营养治疗（NT）对脑卒中后残疾和日常生活活动（ADL）的影响尚未得到充分研究。Sakai等人（2023）的Cochrane综述的目的是评估NT在减少卒中后残疾和改善ADL方面的有效性。本角的目的是从康复的角度对酒井等人的研究进行总结和评论。方法纳入卒中患者的随机对照试验（RCTs），调查NT（定义为补充营养素的管理），与安慰剂、常规护理（UC）或其他类型的NT进行比较。残疾（改良Rankin评分- mrs）和日常生活活动（ADL）是主要指标。该综述包括52项试验（11926名参与者），其中大多数研究在急性期进行（36项），使用了25种补充剂。残疾和全因死亡率没有差异，但口服能量和蛋白质补充剂可能改善ADL。接受NT治疗的患者出现腹泻、高血糖和低血糖的风险较高。结论NT对卒中后残疾和ADL的影响尚不确定，但NT可能与不良事件增加有关。基于理论基础，未来的研究应侧重于有针对性的营养干预以改善脑卒中后的功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

NeuroRehabilitation CLINICAL NEUROLOGY-REHABILITATION

CiteScore

3.20

自引率

0.00%

发文量

178

审稿时长

6-12 weeks

期刊介绍： NeuroRehabilitation, an international, interdisciplinary, peer-reviewed journal, publishes manuscripts focused on scientifically based, practical information relevant to all aspects of neurologic rehabilitation. We publish unsolicited papers detailing original work/research that covers the full life span and range of neurological disabilities including stroke, spinal cord injury, traumatic brain injury, neuromuscular disease and other neurological disorders. We also publish thematically organized issues that focus on specific clinical disorders, types of therapy and age groups. Proposals for thematic issues and suggestions for issue editors are welcomed.