Clinical Efficacy of Sleep Induction Intervention in Conjunction with Lorazepam in Managing Insomnia Disorder.

IF 0.5 4区医学 Q4 PHARMACOLOGY & PHARMACY

Psychiatry and Clinical Psychopharmacology Pub Date : 2025-03-17 eCollection Date: 2025-03-01 DOI:10.5152/pcp.2025.241003

Jing Chen, Yan Zhang, Guoqing Min, Linhui Liu, Lifen Huang, Ji Chen, Jiawei Zhu

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Abstract

Background: This study investigates the clinical efficacy of a combined treatment approach involving sleep induction intervention and lorazepam in managing insomnia disorder.

Methods: This study enrolled a sample of 150 individuals diagnosed with insomnia disorder, consecutively admitted to our clinic from June 2021 to June 2023. Following randomization, the participants were divided into 2 groups: observation and control groups. Both groups were administered lorazepam treatment, with the observation group receiving sleep induction intervention and the control group receiving routine nursing. After the 4-week treatment period, relevant observation indicators were assessed to evaluate the efficacy of sleep improvement in both patient intervention groups.

Results: Compared to the control group that received only lorazepam treatment, the observation group, who underwent sleep induction intervention, showed a better treatment effectiveness rate, sleep quality, and psychological state regarding the treatment of sleep disorders (P < .05).

Conclusion: Sleep induction intervention can improve the overall treatment effectiveness rate of sleep disorders, enhance sleep quality, and alleviate symptoms of anxiety and depression.

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睡眠诱导干预联合劳拉西泮治疗失眠症的临床疗效。

背景：本研究探讨睡眠诱导干预联合劳拉西泮治疗失眠症的临床疗效。方法：本研究招募了150名被诊断为失眠障碍的患者，他们于2021年6月至2023年6月连续入院。随机分组后，将受试者分为观察组和对照组。两组患者均给予劳拉西泮治疗，观察组患者给予睡眠诱导干预，对照组患者给予常规护理。4周治疗期结束后，评估相关观察指标，评价两组患者睡眠改善效果。结果：观察组在睡眠障碍治疗方面的治疗有效率、睡眠质量、心理状态均优于单纯劳拉西泮治疗的对照组（P < 0.05）。结论：睡眠诱导干预可提高睡眠障碍的整体治疗有效率，提高睡眠质量，缓解焦虑、抑郁症状。

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来源期刊

Psychiatry and Clinical Psychopharmacology Medicine-Psychiatry and Mental Health

CiteScore

1.00

自引率

14.30%

发文量

期刊介绍： Psychiatry and Clinical Psychopharmacology aims to reach a national and international audience and will accept submissions from authors worldwide. It gives high priority to original studies of interest to clinicians and scientists in applied and basic neurosciences and related disciplines. Psychiatry and Clinical Psychopharmacology publishes high quality research targeted to specialists, residents and scientists in psychiatry, psychology, neurology, pharmacology, molecular biology, genetics, physiology, neurochemistry, and related sciences.