Treatment outcomes for adolescent bulimia nervosa: a systematic scoping review of quantitative findings.

IF 4.5 3区 医学 Q2 NUTRITION & DIETETICS
Madeleine Love, Julian Baudinet
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Abstract

Background: This study aimed to systematically scope the available quantitative evidence for adolescent Bulimia Nervosa (BN) interventions. Specifically, the study aimed to review psychological and behavioural symptoms outcomes, as well as changes in comorbid psychiatric and caregiver factors.

Method: Five main and three grey literature databases were searched on 4th September 2024. Eligible peer-reviewed journal articles, dissertations and book chapters were included. Studies included children and adolescents with primary diagnoses of Bulimia Nervosa, Eating Disorder Not Otherwise Specified (EDNOS-BN) and Other Specified Feeding and Eating Disorder (OSFED-BN).

Results: Findings from 18 studies (seven randomised controlled trials, three secondary analyses, eight single-arm studies) encompassing 710 participants were synthesised. All studies were conducted in the USA (10/18, 55.6%), UK (4/18, 22.2%), and mainland Europe (4/18, 22.2%). Most were conducted in an outpatient setting (14/18, 77.8%), with the remainder conducted in a day hospital (2/18, 11.1%), mixed outpatient/day hospital (1/18, 5.6%), or residential (1/18, 5.6%) setting. Family-focused therapies (10/18, 55.6%) and cognitive behavioural therapies (10/18, 55.6%) were most represented. Both were associated with improvements in BN psychopathology, comorbid difficulties and parent/caregiver factors. Weak evidence in favour of adjunctive therapies and Fluoxetine were reported.

Discussion: There is a striking paucity in adolescent bulimia nervosa intervention research. Whilst family-focused and cognitive behavioural therapies show promise, the evidence base is relatively small. Most studies had small sample sizes and were conducted with predominately White, female participants. Very little data are available regarding parent/caregiver outcomes. Future research focusing on theory-driven mechanisms that target the broader presentation of BN are needed.

青少年神经性贪食症的治疗结果:定量结果的系统范围综述。
背景:本研究旨在系统地收集青少年神经性贪食症(BN)干预措施的现有定量证据。具体而言,该研究旨在回顾心理和行为症状的结果,以及共病精神和护理因素的变化。方法:于2024年9月4日检索5个主要文献数据库和3个灰色文献数据库。合格的同行评议的期刊文章,论文和书籍章节包括在内。研究对象包括原发性诊断为神经性贪食症、非特异性进食障碍(EDNOS-BN)和其他特异性进食障碍(osfd - bn)的儿童和青少年。结果:综合了18项研究(7项随机对照试验,3项二次分析,8项单臂研究)的结果,包括710名参与者。所有研究均在美国(10/18,55.6%)、英国(4/18,22.2%)和欧洲大陆(4/18,22.2%)进行。大多数在门诊进行(14/18,77.8%),其余在日间医院进行(2/18,11.1%),门诊/日间混合医院(1/18,5.6%)或住院(1/18,5.6%)。以家庭为中心的治疗(10/18,55.6%)和认知行为治疗(10/18,55.6%)最具代表性。两者都与BN精神病理、合并症困难和父母/照顾者因素的改善有关。有微弱的证据支持辅助治疗和氟西汀。讨论:青少年神经性贪食症干预研究明显缺乏。虽然以家庭为中心的认知行为疗法显示出希望,但证据基础相对较小。大多数研究的样本量都很小,参与者主要是白人女性。关于父母/照顾者结果的数据很少。未来的研究重点是理论驱动的机制,目标是BN的更广泛的表现是必要的。
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来源期刊
Journal of Eating Disorders
Journal of Eating Disorders Neuroscience-Behavioral Neuroscience
CiteScore
5.30
自引率
17.10%
发文量
161
审稿时长
16 weeks
期刊介绍: Journal of Eating Disorders is the first open access, peer-reviewed journal publishing leading research in the science and clinical practice of eating disorders. It disseminates research that provides answers to the important issues and key challenges in the field of eating disorders and to facilitate translation of evidence into practice. The journal publishes research on all aspects of eating disorders namely their epidemiology, nature, determinants, neurobiology, prevention, treatment and outcomes. The scope includes, but is not limited to anorexia nervosa, bulimia nervosa, binge eating disorder and other eating disorders. Related areas such as important co-morbidities, obesity, body image, appetite, food and eating are also included. Articles about research methodology and assessment are welcomed where they advance the field of eating disorders.
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