{"title":"Ultra-Low Dose Computed Tomography Imaging in Quantifying Bone Trauma and Disorders: A Cross-Sectional Study.","authors":"Fariba Zarei, Seyedeh Marzieh Ahmadi, Saber Dehbani-Zadeh, Anahita Jafari, Vyas Akondi, Sabyasachi Chatterjee, Seyed Alireza Mirhosseini, Rezvan Ravanfar Haghighi","doi":"10.30476/ijms.2024.102043.3477","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>X-ray computed tomography (CT) is a standard tool for diagnosing bone abnormalities. CT dose optimization is strongly recommended, due to the stochastic effects of x-ray. This study aims to assess the effectiveness of ultra-low-dose CT (ULD-CT) imaging, reconstructed using an Iterative Reconstruction (IR) algorithm, in detecting bone trauma and disorders.</p><p><strong>Methods: </strong>In the present cross-sectional study, 71 patients with CT requests for spine or extremity (limb) bone underwent scanning using standard dose (SD) and ULD-CT protocols, in Shahid Faghihi Hospital, Shiraz, Iran from June 2019 to June 2020. The SD and ULD-CT protocols used 120 kVp and 80 kVp, respectively. The CT images were reconstructed using the standard and IR algorithms. CT dose indices, including the volume CT dose index (CTDI<sub>vol</sub>), dose-length product (DLP), and effective dose (ED), were employed. To assess image quality, a five-point scoring system was used. The sensitivity and specificity of the ULD-CT images were calculated.</p><p><strong>Results: </strong>The findings indicated that ULD-CT images accurately identified 113 out of 118 bone trauma and disorders. The quality of ULD-CT images received \"very good\", \"good\" and \"acceptable\" scores for both spine and extremity (limb) bones. The sensitivity and specificity of ULD-CT images for bone trauma and disorders were 67%-95% and 100%, respectively, with about a 98% dose reduction.</p><p><strong>Conclusion: </strong>The ULD-CT protocol for bone imaging achieved a remarkable dose reduction, while the image quality was reported as acceptable. Consequently, ULD-CT images reconstructed using an IR are suitable and can be tuned further in the future for acceptable use in patients with bone trauma and disorders.</p>","PeriodicalId":14510,"journal":{"name":"Iranian Journal of Medical Sciences","volume":"50 4","pages":"229-238"},"PeriodicalIF":1.5000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008661/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30476/ijms.2024.102043.3477","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: X-ray computed tomography (CT) is a standard tool for diagnosing bone abnormalities. CT dose optimization is strongly recommended, due to the stochastic effects of x-ray. This study aims to assess the effectiveness of ultra-low-dose CT (ULD-CT) imaging, reconstructed using an Iterative Reconstruction (IR) algorithm, in detecting bone trauma and disorders.
Methods: In the present cross-sectional study, 71 patients with CT requests for spine or extremity (limb) bone underwent scanning using standard dose (SD) and ULD-CT protocols, in Shahid Faghihi Hospital, Shiraz, Iran from June 2019 to June 2020. The SD and ULD-CT protocols used 120 kVp and 80 kVp, respectively. The CT images were reconstructed using the standard and IR algorithms. CT dose indices, including the volume CT dose index (CTDIvol), dose-length product (DLP), and effective dose (ED), were employed. To assess image quality, a five-point scoring system was used. The sensitivity and specificity of the ULD-CT images were calculated.
Results: The findings indicated that ULD-CT images accurately identified 113 out of 118 bone trauma and disorders. The quality of ULD-CT images received "very good", "good" and "acceptable" scores for both spine and extremity (limb) bones. The sensitivity and specificity of ULD-CT images for bone trauma and disorders were 67%-95% and 100%, respectively, with about a 98% dose reduction.
Conclusion: The ULD-CT protocol for bone imaging achieved a remarkable dose reduction, while the image quality was reported as acceptable. Consequently, ULD-CT images reconstructed using an IR are suitable and can be tuned further in the future for acceptable use in patients with bone trauma and disorders.
期刊介绍:
The Iranian Journal of Medical Sciences (IJMS) is an international quarterly biomedical publication, which is sponsored by Shiraz University of Medical Sciences. The IJMS intends to provide a scientific medium of communication for researchers throughout the globe. The journal welcomes original clinical articles as well as clinically oriented basic science research experiences on prevalent diseases in the region and analysis of various regional problems.